Conversion of alcohols, thiols, and trimethysilyl ethers to alkyl cyanides using triphenylphosphine/2,3-dichloro-5,6-dicyanobenzoquinone/n-Bu4NCN

被引：66

作者：

Iranpoor, N ^{[1
]}

Firouzabadi, H ^{[1
]}

Akhlaghinia, B ^{[1
]}

Nowrouzi, N ^{[1
]}

机构：

[1] Shiraz Univ, Dept Chem, Shiraz 71454, Iran

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2004年 / 69卷 / 07期

关键词：

D O I：

10.1021/jo035238v

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Triphenylphosphine and 2,3-dichloro-5,6-dicyanobenzoquinone afford an adduct, which in the presence of n-Bu4NCN converts alcohols, thiols, and trimethylsilyl ethers into their corresponding alkyl cyanides in good to excellent yields at room temperature. This method is highly selective for the conversion of 1degrees alcohols in the presence of 2degrees and 3degrees ones, thiols and silyl ethers.

引用

页码：2562 / 2564

页数：3

共 21 条

[1] PREPARATION OF UNSATURATED NITRILES BY THE MODIFICATION OF MITSUNOBU-WILK PROCEDURE .2. CARBON ELONGATION OF BETA-ACETYLENIC ALCOHOLS [J].