The aims were to investigate the prevalence of intramammary infection in early-lactation primiparous dairy cows (PC) in Sweden using milk recording cow composite somatic cell count (CSCC) categories based on classification of CSCC at the first 2 milk recordings after calving as low or high using cut-offs indicating intramarnmary infection. We also wanted to evaluate if herd-specific patterns in CSCC categories among PC can be identified to indicate success and problem herds as well as cow-level associations between CSCC categories and breed and sire, and herd-level associations between CSCC categories and herd size, milk production, production system, milking system, and year. A total of 1,597 dairy herds were included. Inclusion criteria were enrolment in the Swedish official milk recording scheme and having production data from at least 10 PC per year during 2014, 2015, and 2016. Herd (size, SCC, milk production, production system, milking system) and cow (breed, lactation number, calving date, CSCC, milk production) data were collected from the Swedish official milk recording scheme. Each PC was assigned a CSCC category (low-low, low-high, high-high, high-low, or inconclusive) based on the CSCC at the first 2 milk recordings using the following cutoffs. At each milk recording a CSCC <= 75,000 cells/mL was considered low and a CSCC >100,000 cells/mL was considered high, whereas a CSCC in between those values was considered inconclusive. Associations between CSCC categories arid breed or sire of the PC were analyzed using multivariable multinomial logistic regression models. Associations at herd level between number of PC in a CSCC category and herd variables were analyzed using multivariable Poisson or negative binomial regression models. The annual proportions of CSCC categories for all PC were 51.3%, 5.5%, 15.5%, 13.7%, and 14.0% for the low-low, low-high, high-low, high-high, and inconclusive categories, respectively. The distribution of CSCC categories varied markedly between herds. Overall, the median herd prevalence was 50.2 to 54.2% and 11.7 to 13.2% per year for the low-low and high-high categories, respectively. At cow level, both breed and sire were significantly associated with CSCC categories, showing for example that a higher proportion of Jersey PC were categorized as high-high compared with Swedish Holstein (SH) and Swedish Red (SR) PC, and that PC of certain SIT and SR sires more often were categorized as low-low or high-high cows than PC of other sires within each breed. All herd factors, except conventional and organic production, were significantly associated with the proportion of PC in a CSCC category at herd level. For example, the proportion of PC in the low-low category was significantly lower in larger herds (>80 cows) compared with smaller herds (<80 cows) and significantly lower in automatic milking system herds than in herds with other milking systems, but significantly higher in herds with higher milk production. Overall, the results indicate a substantial need for prevention of sub-clinical mastitis in early-lactation PC as only 50% of these cows had low CSCC at both milk recordings after calving. Moreover, we conclude that CSCC categories may be a useful tool for identifying success and problem herds.
