ST-Elevation Myocardial Infarction in Patients ≤35 Years of Age

被引:12
作者
Ruiz Pizarro, Virginia [1 ]
Palacios-Rubio, Julian [1 ]
Cruz-Utrilla, Alejandro [1 ]
Garcia-Arribas, Daniel [1 ]
Jose Perez-Vizcayno, Maria [1 ]
Fernandez-Ortiz, Antonio [1 ]
Javier Nunez-Gil, Ivan [1 ]
机构
[1] Hosp Clin San Carlos, Inst Cardiovasc, Madrid, Spain
关键词
CORONARY-ARTERY-DISEASE; YOUNG-PATIENTS; RISK-FACTORS; GUIDELINES; PROGNOSIS; ADULTS;
D O I
10.1016/j.amjcard.2018.12.017
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
ST-elevation myocardial infarction (STEMI) in very young patients is an uncommon entity but with significant clinical meaning for the patient. These individuals may have different risk profiles and prognosis. Few reports have described epidemiology, clinical features, and long-term outcomes of these patients in the era of percutaneous coronary intervention, particularly of those <= 35. This observational study evaluates the clinical characteristics of patients < 35 years with STEM! between January 2004 and September 2016 in 3 different centers. We gathered data and follow-up from the prospective database of the interventional cardiology department, medical history, and phone interviews. Over a total of 3,883 STEMI, we retrieved 61 patients <= 35. They were mainly male (88%), smokers (80%), and overweight (67%). Twenty-six percent were drug consumers. Only 2 patients (3%) were free of conventional risk factors. In-hospital mortality was 5% (3 deaths). They were followed-up for 5.9 +/- 4.2 years with a total survival of 96.6% (2 deaths). Major adverse cardiovascular events incidence at the end of follow-up was only 17.2% (10 patients). STEMI in the young is a rare condition. These patients have several modifiable predisposing factors, a low clinical risk profile, and excellent short- and long-term prognosis with state-of-the-art treatment. (C) 2018 Elsevier Inc. All rights reserved.
引用
收藏
页码:889 / 893
页数:5
相关论文
共 24 条
[1]   2007 focused update of the ACC/AHA 2004 guidelines for the management of patients with ST-elevation myocardial infarction - A report of the American college of cardiology/American heart association task force on practice guidelines [J].
Antman, Elliott M. ;
Hand, Mary ;
Armstrong, Paul W. ;
Bates, Eric R. ;
Green, Lee A. ;
Halasyamani, Lakshmi K. ;
Hochman, Judith S. ;
Krumholz, Harlan M. ;
Lamas, Gervasio A. ;
Mullany, Charles J. ;
Pearle, David L. ;
Sloan, Michael A. ;
Smith, Sidney C., Jr. .
CIRCULATION, 2008, 117 (02) :296-329
[2]   Long-term follow-up of coronary artery disease presenting in young adults [J].
Cole, JH ;
Miller, JI ;
Sperling, LS ;
Weintraub, WS .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2003, 41 (04) :521-528
[3]   CORONARY-ARTERY DISEASE IN YOUNG PATIENTS - ARTERIOGRAPHIC AND CLINICAL REVIEW OF 40 CASES AGED 35 AND UNDER [J].
DAVIA, JE ;
HALLAL, FJ ;
CHEITLIN, MD ;
GREGORATOS, G ;
MCCARTY, R ;
FOOTE, W .
AMERICAN HEART JOURNAL, 1974, 87 (06) :689-696
[4]   Cocaine and Marijuana Use Among Young Adults With Myocardial Infarction [J].
DeFilippis, Ersilia M. ;
Singh, Avinainder ;
Divakaran, Sanjay ;
Gupta, Ankur ;
Collins, Bradley L. ;
Biery, David ;
Qamar, Arman ;
Fatima, Amber ;
Ramsis, Mattheus ;
Pipilas, Daniel ;
Rajabi, Roxanna ;
Eng, Monica ;
Hainer, Jon ;
Klein, Josh ;
Januzzi, James L. ;
Nasir, Khurram ;
Di Carli, Marcelo F. ;
Bhatt, Deepak L. ;
Blankstein, Ron .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2018, 71 (22) :2540-2551
[5]   Acute myocardial infarction in the young - The University of Michigan experience [J].
Doughty, M ;
Mehta, R ;
Bruckman, D ;
Das, S ;
Karavite, D ;
Tsai, T ;
Eagle, K .
AMERICAN HEART JOURNAL, 2002, 143 (01) :56-62
[6]   Myocardial infarction in young adults [J].
Egred, M ;
Viswanathan, G ;
Davis, GK .
POSTGRADUATE MEDICAL JOURNAL, 2005, 81 (962) :741-745
[7]   Myocardial infarction in men aged 40 years or less: A prospective clinical-angiographic study [J].
Fournier, JA ;
Sanchez, A ;
Quero, J ;
FernandezCortacero, JAP ;
GonzalezBarrero, A .
CLINICAL CARDIOLOGY, 1996, 19 (08) :631-636
[8]  
Gabriel R, 2008, REV ESP CARDIOL, V61, P1030, DOI 10.1016/S1885-5857(09)60006-2
[9]   Variation of lipoprotein(a) plasma levels after premature myocardial infarction [J].
Goliasch, Georg ;
Wiesbauer, Franz ;
Blessberger, Hermann ;
Maurer, Gerald ;
Derfler, Kurt ;
Speidl, Walter S. .
INTERNATIONAL JOURNAL OF CARDIOLOGY, 2015, 186 :5-6
[10]   Predictors of hospital mortality in the global registry of acute coronary events [J].
Granger, CB ;
Goldberg, RJ ;
Dabbous, O ;
Pieper, KS ;
Eagle, KA ;
Cannon, CP ;
Van de Werf, F ;
Avezum, A ;
Goodman, SG ;
Flather, MD ;
Fox, KAA .
ARCHIVES OF INTERNAL MEDICINE, 2003, 163 (19) :2345-2353