Evaluation of three immunochromatographic kits for rapid detection of influenza virus A and B

被引：8

作者：

Hara, Michimaru ^{[1
]}

Takao, Shinichi ^{[2
]}

Fukuda, Shinji ^{[2
]}

Shimazu, Yuki ^{[2
]}

Miyazaki, Kazuo ^{[2
]}

机构：

[1] Hiroshima Prefectural Inst Publ Hlth & Environm, Hara Pediat Clin, Hiroshima, Japan

[2] Hiroshima Prefectural Inst Publ Hlth & Environm, Dept Microbiol, Hiroshima, Japan

来源：

LABMEDICINE | 2008年 / 39卷 / 10期

关键词：

D O I：

10.1309/LM6ONMGY7K9ETMGF

中图分类号：

R446 [实验室诊断]; R-33 [实验医学、医学实验];

学科分类号：

1001 ;

摘要：

Background: Clinically, it is difficult to distinguish influenza infection from febrile infections caused by respiratory syncytial virus, adenovirus, rhinovirus, and human metapneumovirus without the use of rapid diagnostic tests. Methods: Nasopharyngeal aspirates (NPAs) were collected from 494 pediatric patients and were tested for the presence of influenza A and B virus antigen using 3 rapid diagnotic kits: ESPLINE Influenza A and B-N, Directigen EZ Flu A and B, and Binax NOW Influenza A and B. Results: Fifty-three specimens positive by viral culture were positive for influenza A by all 3 kits. Of the 270 influenza B virus cell-culture-positive specimens, the sensitivities of ESPLINE, EZ, and NOW were 86%, 76%, and 78%, respectively. Conclusion: Under well controlled conditions, influenza A virus sensitivities for all 3 kits can be 100% with specificities ranging from 98% to 100%.

引用

页码：603 / 606

页数：4

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