Peptide Receptor Radionuclide Therapy (PRRT) in a Patient Affected by Metastatic Breast Cancer with Neuroendocrine Differentiation

被引：29

作者：

Savelli, Giordano ^{[1
]}

Zaniboni, Alberto ^{[2
]}

Bertagna, Francesco ^{[3
]}

Bosio, Giovanni ^{[3
]}

Nisa, Lutfun ^{[3
]}

Rodella, Carlo ^{[3
]}

Biasiotto, Giorgio ^{[3
]}

Bettinsoli, Giovanni ^{[3
]}

Migliorati, Elena ^{[3
]}

Peli, Alessia ^{[3
]}

Falchi, Roberta ^{[1
]}

Giuffrida, Francesca ^{[1
]}

Giubbini, Raffaele ^{[3
]}

机构：

[1] Mantua Civ Hosp Carlo Poma, Nucl Med Unit, I-46100 Mantua, Italy

[2] IC Fdn Poliambulanza, Div Oncol, Brescia, Italy

[3] Spedali Civili Hosp, Nucl Med Unit, Brescia, Italy

来源：

BREAST CARE | 2012年 / 7卷 / 05期

关键词：

Radionuclide therapy; Peptide receptors; SOMATOSTATIN; EXPRESSION; CARCINOMA; TUMORS; Y-90-DOTATOC; SCINTIGRAPHY;

D O I：

10.1159/000343612

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Background: Breast cancer (BC) is the most frequent cancer in European women with nearly 30% of the patients eventually developing metastases. Neuroendocrine differentiation is a rare event, but overexpression of somatostatin receptors in BC has been reported in many studies. Case Report: A patient with liver metastases from BC was treated with peptide receptor radio-nuclide therapy (PRRT). Computed tomography scan and biochemical examinations showed a clear response to radionuclide therapy. Conclusion: PRRT may be useful in metastatic BC patients.

引用

页码：408 / 410

页数：3

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