Sepsis-Induced Tissue Hypoperfusion

被引:13
作者
Jones, Alan E. [1 ]
Puskarich, Michael A. [1 ]
机构
[1] Carolinas Med Ctr, Dept Emergency Med, Charlotte, NC 28203 USA
关键词
Sepsis; Septic shock; Resuscitation; Lactate; Hypoperfusion; Infection; Emergency; VENOUS OXYGEN-SATURATION; BENCH-TO-BEDSIDE; PULMONARY-ARTERY CATHETER; BLOOD LACTATE LEVELS; ORGAN FAILURE; SEPTIC SHOCK; HEMODYNAMIC OPTIMIZATION; SUBLINGUAL CAPNOMETRY; UNITED-STATES; MORTALITY;
D O I
10.1016/j.ccell.2010.12.007
中图分类号
R47 [护理学];
学科分类号
1011 ;
摘要
Sepsis affects the cardiovascular system through multiple mechanisms, and often these derangements result in tissue hypoperfusion. Tissue hypoperfusion is often present in the setting of overt shock, but it can also be present in patients without obvious shock physiology. If left untreated, tissue hypoperfusion contributes to the development of multiple organ dysfunction and, ultimately, death. Therefore, it is critical for the clinician to understand the pathophysiology, recognition, and treatment of sepsis-induced hypoperfusion.
引用
收藏
页码:115 / +
页数:12
相关论文
共 50 条
  • [41] Glycocalyx and sepsis-induced alterations in vascular permeability
    Chelazzi, Cosimo
    Villa, Gianluca
    Mancinelli, Paola
    De Gaudio, A. Raffaele
    Adembri, Chiara
    CRITICAL CARE, 2015, 19
  • [42] Inhibition of sepsis-induced inflammatory response by β1-adrenergic antagonists
    Ibrahim-zada, Irada
    Rhee, Peter
    Gomez, Christopher T.
    Weller, John
    Friese, Randall S.
    JOURNAL OF TRAUMA AND ACUTE CARE SURGERY, 2014, 76 (02) : 320 - 328
  • [43] Sepsis-Induced Cardiomyopathy Detected With Focused Cardiac Ultrasound in the Emergency Department
    V. Tucker, Ryan
    Williams, Kendrick
    Theyyunni, Nik
    Fung, Christopher M.
    JOURNAL OF EMERGENCY MEDICINE, 2022, 63 (04) : E91 - E99
  • [44] Tissue Kallikrein Exacerbating Sepsis-Induced Endothelial Hyperpermeability is Highly Predictive of Severity and Mortality in Sepsis
    Ran, Xiao
    Zhang, Qin
    Li, Shaoping
    Yu, Zhen
    Wan, Li
    Wu, Bin
    Wu, Rongxue
    Li, Shusheng
    JOURNAL OF INFLAMMATION RESEARCH, 2021, 14 : 3321 - 3333
  • [45] Sepsis-induced changes in pyruvate metabolism: insights and potential therapeutic approaches
    Nuyttens, Louise
    Vandewalle, Jolien
    Libert, Claude
    EMBO MOLECULAR MEDICINE, 2024, 16 (11) : 2678 - 2698
  • [46] Prevalence and risk factors of sepsis-induced cardiomyopathy: A retrospective cohort study
    Sato, Ryota
    Kuriyama, Akira
    Takada, Tadaaki
    Nasu, Michitaka
    Luthe, Sarah Kyuragi
    MEDICINE, 2016, 95 (39)
  • [47] Pathophysiology of sepsis-induced cardiomyopathy
    Hollenberg, Steven M.
    Singer, Mervyn
    NATURE REVIEWS CARDIOLOGY, 2021, 18 (06) : 424 - 434
  • [48] Feasibility and discriminatory value of tissue motion annular displacement in sepsis-induced cardiomyopathy: a single-center retrospective observational study
    Song, Jieqiong
    Yao, Yao
    Lin, Shilong
    He, Yizhou
    Zhu, Duming
    Zhong, Ming
    CRITICAL CARE, 2022, 26 (01)
  • [49] Association of sepsis-induced cardiomyopathy and mortality: a systematic review and meta-analysis
    Lin, Yu-Min
    Lee, Mei-Chuan
    Toh, Han Siong
    Chang, Wei-Ting
    Chen, Sih-Yao
    Kuo, Fang-Hsiu
    Tang, Hsin-Ju
    Hua, Yi-Ming
    Wei, Dongmei
    Melgarejo, Jesus
    Zhang, Zhen-Yu
    Liao, Chia-Te
    ANNALS OF INTENSIVE CARE, 2022, 12 (01)
  • [50] Preventative Management of Sepsis-Induced Acute Respiratory Distress Syndrome in the Geriatric Population
    Geyer-Roberts, Elizabeth
    Lacatusu, Diana A.
    Kester, Jessica
    Foster-Moumoutjis, Gina
    Sidiqi, Mojda
    CUREUS JOURNAL OF MEDICAL SCIENCE, 2023, 15 (02)