Actin in hair cells and hearing loss

被引：52

作者：

Drummond, Meghan C. ^{[1
]}

Belyantseva, Inna A. ^{[1
]}

Friderici, Karen H. ^{[2
]}

Friedman, Thomas B. ^{[1
]}

机构：

[1] Natl Inst Deafness & Other Commun Disorders, Mol Genet Lab, NIH, Rockville, MD 20850 USA

[2] Michigan State Univ, Dept Microbiol & Mol Genet, Dept Pediat & Human Dev, E Lansing, MI 48824 USA

来源：

HEARING RESEARCH | 2012年 / 288卷 / 1-2期

关键词：

NONSYNDROMIC RECESSIVE DEAFNESS; GENOTYPE-PHENOTYPE CORRELATION; CYTOPLASMIC GAMMA-ACTIN; USHER-SYNDROME PROTEINS; MYOSIN-VIIA GENE; BETA-ACTIN; INNER-EAR; AUTOSOMAL-DOMINANT; UNCONVENTIONAL MYOSIN; TIP-LINK;

D O I：

10.1016/j.heares.2011.12.003

中图分类号：

R36 [病理学]; R76 [耳鼻咽喉科学];

学科分类号：

100104 ; 100213 ;

摘要：

Hereditary deafness is genetically heterogeneous such that mutations of many different genes can cause hearing loss. This review focuses on the evidence and implications that several of these deafness genes encode actin-interacting proteins or actin itself. There is a growing appreciation of the contribution of the actin interactome in stereocilia development, maintenance, mechanotransduction and malfunction of the auditory system. Published by Elsevier B.V.

引用

页码：89 / 99

页数：11

共 158 条

[111] Life at the Leading Edge [J].

Ridley, Anne J. .

CELL, 2011, 145 (07) :1012-1022

[112]

Riviere J.B., 2011, 12 INT C HUM GEN AM

[113] Regulation of actin cytoskeleton architecture by Eps8 and Abi1 [J].

Roffers-Agarwal, J ;

Xanthos, JB ;

Miller, JR .

BMC CELL BIOLOGY, 2005, 6 (1)

[114] Characterization of a beta-actin mRNA zipcode-binding protein [J].

Ross, AF ;

Oleynikov, Y ;

Kislauskis, EH ;

Taneja, KL ;

Singer, RH .

MOLECULAR AND CELLULAR BIOLOGY, 1997, 17 (04) :2158-2165

[115] Myosin VI is required for the proper maturation and function of inner hair cell ribbon synapses [J].

Roux, Isabelle ;

Hosie, Suzanne ;

Johnson, Stuart L. ;

Bahloul, Amel ;

Cayet, Nadege ;

Nouaille, Sylvie ;

Kros, Corne J. ;

Petit, Christine ;

Safieddine, Saaid .

HUMAN MOLECULAR GENETICS, 2009, 18 (23) :4615-4628

[116] MyosinVIIa Interacts with Twinfilin-2 at the Tips of Mechanosensory Stereocilia in the Inner Ear [J].

Rzadzinska, Agnieszka K. ;

Nevalainen, Elisa M. ;

Prosser, Haydn M. ;

Lappalainen, Pekka ;

Steel, Karen P. .

PLOS ONE, 2009, 4 (09)

[117] An actin molecular treadmill and myosins maintain stereocilia functional architecture and self-renewal [J].

Rzadzinska, AK ;

Schneider, ME ;

Davies, C ;

Riordan, GP ;

Kachar, B .

JOURNAL OF CELL BIOLOGY, 2004, 164 (06) :887-897

[118] Dynamic compartmentalization of protein tyrosine phosphatase receptor Q at the proximal end of stereocilia: Implication of myosin VI-based transport [J].

Sakaguchi, Hirofumi ;

Tokita, Joshua ;

Naoz, Moshe ;

Bowen-Pope, Daniel ;

Gov, Nir S. ;

Kachar, Bechara .

CELL MOTILITY AND THE CYTOSKELETON, 2008, 65 (07) :528-538

[119] A novel nonsense mutation in MYO6 is associated with progressive nonsyndromic hearing loss in a Danish DFNA22 family [J].

Sanggaard, Kirsten M. ;

Kjaer, Klaus W. ;

Eiberg, Hans ;

Nuernberg, Gudrun ;

Nuernberg, Peter ;

Hoffman, Katrin ;

Jensen, Henne ;

Sorum, Charlotte ;

Rendtorff, Nanna D. ;

Tranebjaerg, Lisbeth .

AMERICAN JOURNAL OF MEDICAL GENETICS PART A, 2008, 146A (08) :1017-1025

[120] Structural cell biology: Rapid renewal of auditory hair bundles - The recovery time after noise-induced hearing loss is in step with a molecular treadmill. [J].

Schneider, ME ;

Belyantseva, IA ;

Azevedo, RB ;

Kachar, B .

NATURE, 2002, 418 (6900) :837-838

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