AHEAD score - Long-term risk classification in acute heart failure

被引：68

作者：

Spinar, Jindrich ^{[1
,2
,3
]}

Jarkovsky, Jiri ^{[4
]}

Spinarova, Lenka ^{[2
,5
]}

Mebazaa, Alexandre ^{[6
,7
]}

Gayat, Etienne ^{[6
,7
]}

Vitovec, Jiri ^{[2
,5
]}

Linhart, Ales ^{[8
,9
]}

Widimsky, Petr ^{[10
,11
]}

Miklik, Roman ^{[1
,3
]}

Zeman, Kamil ^{[12
]}

Belohlavek, Jan ^{[8
,9
]}

Malek, Filip ^{[13
]}

Felsoci, Marian ^{[1
,2
,3
]}

Kettner, Jiri ^{[14
]}

Ostadal, Petr ^{[13
]}

Cihalik, Cestmir ^{[15
]}

Vaclavik, Jan ^{[15
]}

Taborsky, Milos ^{[15
]}

Dusek, Ladislav ^{[4
]}

Littnerova, Simona ^{[4
]}

Parenica, Jiri ^{[1
,2
,3
]}

机构：

[1] Univ Hosp Brno, Dept Cardiol, Brno 62500, Czech Republic

[2] Masaryk Univ, Fac Med, Brno, Czech Republic

[3] Univ Hosp St Annes, Int Clin Res Ctr, Dept Cardiovasc Dis, Brno, Czech Republic

[4] Masaryk Univ, Fac Med, Inst Biostat & Anal, Brno, Czech Republic

[5] Univ Hosp St Annes, Dept Cardiovasc Internal Med 1, Brno, Czech Republic

[6] St Louis Lariboisiere Univ Hosp, Dept Anesthesiol & Crit Care Med, Paris, France

[7] INSERM, UMR S 942, Paris, France

[8] Charles Univ Prague, Fac Med 1, Dept Cardiovasc Internal Med 2, Prague, Czech Republic

[9] Gen Teaching Hosp Prague, Prague, Czech Republic

[10] Charles Univ Prague, Kralovske Vinohrady Univ Hosp, Prague, Czech Republic

[11] Charles Univ Prague, Fac Med 3, Prague, Czech Republic

[12] Hosp Frydek Mistek, Dept Internal Med, Frydek Mystek, Czech Republic

[13] Homolce Hosp, Dept Cardiol, Prague, Czech Republic

[14] Inst Clin & Expt Med, Dept Cardiol, Prague, Czech Republic

[15] Univ Hosp Olomouc, Dept Internal Med, Olomouc, Czech Republic

来源：

INTERNATIONAL JOURNAL OF CARDIOLOGY | 2016年 / 202卷

关键词：

Acute heart failure; Prognosis; Model; Mortality; IN-HOSPITAL MORTALITY; PREDICTING MORTALITY; ATRIAL-FIBRILLATION; TREATMENT OPTIONS; TASK-FORCE; ANEMIA; ASSOCIATION; GUIDELINES; STRATIFICATION; POPULATION;

D O I：

10.1016/j.ijcard.2015.08.187

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Background: The role of co-morbidities in the prognosis of patients hospitalized for AHF was examined using the AHEAD (A - atrial fibrillation, H - haemoglobin < 130 g/l for men and 120 g/l for women (anaemia), E - elderly (age > 70 years), A - abnormal renal parameters (creatinine > 130 mu mol/l), D - diabetes mellitus) scoring system. Methods: AHEAD - multicentre prospective Czech registry of AHF patients; GREAT registry - international cohort of AHF patients. Data from 5846 consecutive patients hospitalized for AHF (AHEAD registry; derivation cohort) were analysed to build the AHEAD score. Each risk factor of the AHEAD score was counted as 1 point. The model was validated externally using an international cohort of similar patients in the GREAT registry (6315). Results: Main outcome was one year all-cause mortality. The mean age of patients was 72 +/- 12 years, with 61.6% of patients aged > 70 years; 43.4% were women. Atrial fibrillation was present in 30.7%, anaemia in 38.2%, creatinine > 130 mmol/l (abnormal renal parameters) in 30.1%, and diabetes mellitus in 44.0%. The mean AHEAD score was 2.1. In patients with AHEAD scores of 0-5, the one-year mortality rates were 13.6%, 23.4%, 32.0%, 41.1%, 47.7%, and 58.2%, respectively (p < 0.001), and the 90 month mortality rates were 35.1%, 57.3%, 73.5%, 84.8%, 88.0%, and 91.7%, respectively (p < 0.001). Conclusion: The AHEAD is a simple scoring system based on the analysis of co-morbidities for the estimation of the short and long term prognosis of patients hospitalized for AHF. (C) 2015 Elsevier Ireland Ltd. All rights reserved.

引用

页码：21 / 26

页数：6

共 31 条

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