Downstream processing of acetate fermentation broths by nanofiltration

被引:21
作者
Han, IS [1 ]
Cheryan, M [1 ]
机构
[1] UNIV ILLINOIS,AGR BIOPROC LAB,URBANA,IL 61801
关键词
acetate; membrane technology; nanofiltration; separation;
D O I
10.1007/BF02941684
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Acetate can be separated from fermentation broths and partially purified by nanofiltration (NF). Membrane performance was a function of pressure, pH, concentration of acetate, temperature, and the presence of other media components. With Nitto-Denko's NTR729 membrane, average acetate rejection was 60%, glucose rejection was 99%, and flux was 15 L/m(2)/h at 200 psig, 30 degrees C, pH 5.6, and 20 g/L acetic acid. The best downstream strategy is to clarify the fermentation broth by microfiltration (MF), recycle the cells for improving fermenter productivity, nanofilter the cell-free broth, and then evaporate the permeate. The cost of ceramic MF and NF purification is about $66/t acetate, compared to the cost of potassium acetate ($950/t) or calcium-magnesium acetate ($700/t).
引用
收藏
页码:19 / 28
页数:10
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