Intense physical activity is associated with cognitive performance in the elderly

被引：95

作者：

Brown, B. M. ^{[1
,2
,3
]}

Peiffer, J. J. ^{[1
,4
]}

Sohrabi, H. R. ^{[1
,2
,3
]}

Mondal, A. ^{[1
,3
]}

Gupta, V. B. ^{[1
,3
]}

Rainey-Smith, S. R. ^{[1
,3
]}

Taddei, K. ^{[1
,3
]}

Burnham, S. ^{[5
]}

Ellis, K. A. ^{[6
,7
,8
]}

Szoeke, C. ^{[9
]}

Masters, C. L. ^{[6
]}

Ames, D. ^{[7
,8
]}

Rowe, C. C. ^{[10
,11
]}

Martins, R. N. ^{[1
,2
,3
]}

机构：

[1] Edith Cowan Univ, Sch Med Sci, Ctr Excellence Alzheimers Dis Res & Care, Joondalup, WA 6027, Australia

[2] Univ Western Australia, Sch Psychiat & Clin Neurosci, Nedlands, WA 6009, Australia

[3] Hollywood Private Hosp, McCusker Alzheimers Res Fdn, Hollywood Med Ctr, Nedlands, WA, Australia

[4] Murdoch Univ, Sch Psychol & Exercise Sci, Murdoch, WA 6150, Australia

[5] CSIRO, Preventat Hlth Flagship Math Informat & Stat, Floreat, WA, Australia

[6] Univ Melbourne, Mental Hlth Res Inst, Parkville, Vic 3052, Australia

[7] Natl Ageing Res Inst, Parkville, Vic, Australia

[8] Univ Melbourne, St Vincents Aged Psychiat Serv, St Georges Hosp, Acad Unit Psychiat Old Age,Dept Psychiat, Carlton, Vic 3053, Australia

[9] Univ Melbourne, Dept Psychiat, Carlton, Vic 3053, Australia

[10] Austin Hlth, Dept Nucl Med, Heidelberg, Vic, Australia

[11] Austin Hlth, Ctr PET, Heidelberg, Vic, Australia

来源：

TRANSLATIONAL PSYCHIATRY | 2012年 / 2卷

基金：

英国医学研究理事会;

关键词：

Alzheimer's disease; cognition; exercise; physical activity; NEUROTROPHIC FACTOR; ALZHEIMERS-DISEASE; ACTIVITY QUESTIONNAIRE; CORTICAL PLASTICITY; HEART-DISEASE; OLDER-ADULTS; EXERCISE; BRAIN; DECLINE; POPULATION;

D O I：

10.1038/tp.2012.118

中图分类号：

R749 [精神病学];

学科分类号：

100205 ;

摘要：

Numerous studies have reported positive impacts of physical activity on cognitive function. However, the majority of these studies have utilised physical activity questionnaires or surveys, thus results may have been influenced by reporting biases. Through the objective measurement of routine levels of physical activity via actigraphy, we report a significant association between intensity, but not volume, of physical activity and cognitive functioning. A cohort of 217 participants (aged 60-89 years) wore an actigraphy unit for 7 consecutive days and underwent comprehensive neuropsychological assessment. The cohort was stratified into tertiles based on physical activity intensity. Compared with individuals in the lowest tertile of physical activity intensity, those in the highest tertile scored 9%, 9%, 6% and 21% higher on the digit span, digit symbol, Rey Complex Figure Test (RCFT) copy and Rey Figure Test 30-min recall test, respectively. Statistically, participants in the highest tertile of physical activity intensity performed significantly better on the following cognitive tasks: digit symbol, RCFT copy and verbal fluency test (all P<0.05). The results indicate that intensity rather than quantity of physical activity may be more important in the association between physical activity and cognitive function.

引用

页码：e191 / e191

页数：6

共 45 条

[1] Voluntary exercise protects against stress-induced decreased in brain-derived neurotrophic factor protein expression [J].