Revascularization options in stable coronary artery disease: it is not how to revascularize, it is whether and when to revascularize

被引：2

作者：

Torosoff, Mikhail T. ^{[1
,2
]}

Sidhu, Mandeep S. ^{[1
,2
,3
]}

Desai, Karan P. ^{[4
]}

Fein, Steven A. ^{[1
,2
]}

Boden, William E. ^{[1
,2
,3
]}

机构：

[1] Albany Med Ctr, Dept Med, Div Cardiol, Albany, NY 12208 USA

[2] Albany Med Coll, Albany, NY 12208 USA

[3] Samuel S Stratton VA Med Ctr, Albany, NY USA

[4] Johns Hopkins Sch Med, Dept Med, Baltimore, MD USA

来源：

JOURNAL OF COMPARATIVE EFFECTIVENESS RESEARCH | 2015年 / 4卷 / 05期

关键词：

coronary anatomy; coronary artery disease; ischemia; myocardial ischemia; optimal medical therapy; revascularization; stable ischemic heart disease; OPTIMAL MEDICAL THERAPY; CONTROLLED CLINICAL-TRIAL; FRACTIONAL FLOW RESERVE; OUTCOMES UTILIZING REVASCULARIZATION; 10-YEAR FOLLOW-UP; QUALITY-OF-LIFE; MASS-II; MYOCARDIAL-ISCHEMIA; COST-EFFECTIVENESS; STENT THROMBOSIS;

D O I：

10.2217/cer.15.37

中图分类号：

R19 [保健组织与事业（卫生事业管理）];

学科分类号：

摘要：

Patients with acute coronary syndromes and severe multivessel or left main coronary artery disease have better outcomes when prompt revascularization is performed in addition to optimal medical therapy (OMT). However, in patients with stable ischemic heart disease, randomized strategy trials have revealed equipoise between initial strategies of OMT alone and OMT plus revascularization. Conducted in diverse stable ischemic heart disease patient populations and throughout the spectrum of atherosclerotic and ischemic burden, the RITA-2, MASS II, COURAGE, BARI 2D and FAME 2 trials demonstrate that OMT alone and OMT plus revascularization yield similar outcomes with respect to mortality and myocardial infarction. What remains unclear is whether there may be one or more subsets of patients with stable ischemic heart disease in whom revascularization may be associated with a reduction in mortality or myocardial infarction, which is to be addressed in the ongoing ISCHEMIA trial.

引用

页码：505 / 514

页数：10

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