Skin Immunity

被引：123

作者：

Matejuk, Agata ^{[1
,2
]}

机构：

[1] Wroclaw Med Univ, Fac Hlth Sci, Wroclaw, Poland

[2] Karkonosze Coll, Fac Sci & Technol, Jelenia Gora, Poland

来源：

ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS | 2018年 / 66卷 / 01期

关键词：

Immune response; Skin; Epidermis; Dermis; Hypoxia; REGULATORY T-CELLS; EPIDERMAL LANGERHANS CELLS; ANTIGEN-PRESENTING CELLS; DERMAL DENDRITIC CELLS; INTERLEUKIN-12/23; MONOCLONAL-ANTIBODY; PROTEINASE-ACTIVATED RECEPTOR-2; ALLERGIC CONTACT-DERMATITIS; HUMAN MAST-CELLS; IN-VIVO; ATOPIC-DERMATITIS;

D O I：

10.1007/s00005-017-0477-3

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Skin is the largest organ of the body with a complex network of multitude of cell types that perform plastic and dynamic cellular communication to maintain several vital processes such as inflammation, immune response including induction of tolerance and disease prevention, wound healing, and angiogenesis. Of paramount importance are immunological functions of the skin that protect from harmful exposure coming from external and internal environments. Awareness of skin immunity can provide a better comprehension of inflammation, autoimmunity, cancer, graft-versus-host disease, vaccination, and immunotherapy approaches. This paper will update on what we currently know about immune sentinels contributing to skin immunity.

引用

页码：45 / 54

页数：10

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