Leptin and puberty

被引:23
|
作者
Urbanski, HF [1 ]
机构
[1] Oregon Reg Primate Res Ctr, Div Neurosci, Beaverton, OR 97006 USA
来源
TRENDS IN ENDOCRINOLOGY AND METABOLISM | 2001年 / 12卷 / 10期
基金
美国国家卫生研究院;
关键词
D O I
10.1016/S1043-2760(01)00505-7
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Leptin is thought to relay metabolic information to the hypothalamic-pituitary-gonadal axis and to participate in the neuroendocrine control of puberty. To help elucidate the underlying mechanism, Cheung et al. recently performed a diverse series of experiments, the results of which undermine the prevailing hypothesis that leptin acts as a metabolic trigger for the initiation of puberty. Instead,their results suggest that leptin is one of many permissive metabolic factors that allow pubertal development to proceed.
引用
收藏
页码:428 / 429
页数:2
相关论文
共 50 条
  • [41] A reassessment of leptin's role in triggering the onset of puberty in the rat and mouse
    Cheung, CC
    Thornton, JE
    Nurani, SD
    Clifton, DK
    Steiner, RA
    NEUROENDOCRINOLOGY, 2001, 74 (01) : 12 - 21
  • [42] Association of ghrelin and leptin with reproductive hormones in constitutional delay of growth and puberty
    Mervat M El-Eshmawy
    Ibrahim A Abdel Aal
    Amany K El hawary
    Reproductive Biology and Endocrinology, 8
  • [43] Genetic relationships of body composition, serum leptin, and age at puberty in gilts
    Kuehn, L. A.
    Nonneman, D. J.
    Klindt, J. M.
    Wise, T. H.
    JOURNAL OF ANIMAL SCIENCE, 2009, 87 (02) : 477 - 483
  • [44] HYPERLEPTINAEMIA WITH POSSIBLE LEPTIN-RESISTANCE IN OBESE BOYS WITH DELAYED PUBERTY
    Atwa, H.
    ACTA PAEDIATRICA, 2009, 98 : 80 - 80
  • [45] Longitudinal study of the simultaneous secretion of melatonin and leptin during normal puberty
    Molina-Carballo, A.
    Fernandez-Tardaguila, E.
    Uberos-Fernandez, J.
    Seiquer, I.
    Contreras-Chova, F.
    Munoz-Hoyos, A.
    HORMONE RESEARCH, 2007, 68 (01) : 11 - 19
  • [46] Effects of GH and leptin plasma levels on puberty in Sarda breed goats
    Carcangiu, V.
    Vacca, G. M.
    Pazzola, M.
    Parmeggiani, A.
    Mura, M. C.
    Dettori, M. L.
    Bini, P. P.
    REPRODUCTION IN DOMESTIC ANIMALS, 2007, 42 : 141 - 141
  • [47] Study of leptin levels and gene polymorphisms in patients with central precocious puberty
    Pen-Hua Su
    Shun-Fa Yang
    Ju-Shan Yu
    Suh-Jen Chen
    Jia-Yuh Chen
    Pediatric Research, 2012, 71 : 361 - 367
  • [48] Hyperleptinaemia with possible leptin-resistance in obese boys with delayed puberty
    Atwa, Hoda Ahmed
    Wasfi, Roshdy Mohamed
    Atwa, Mona Ahmed
    Fathy, Amal
    Fateh-Elbab, Mohamed
    HORMONE RESEARCH, 2009, 72 : 138 - 139
  • [49] The potential role of periovarian fat and leptin in initiation of puberty in the immature rat
    WE Cannady
    DW Brann
    VB Mahesh
    International Journal of Obesity, 2000, 24 : S146 - S147
  • [50] Puberty in female mice is not associated with increases in either body fat or leptin
    Bronson, FH
    ENDOCRINOLOGY, 2001, 142 (11) : 4758 - 4761