Synthesis and chemical transformations of 3-acetyl-4-hydroxyquinolin-2(1H)-one and its N-substituted derivatives: bird's eye view

被引：16

作者：

Abdou, Moaz M. ^{[1
,2
,3
]}

Seferoglu, Zeynel ^{[4
]}

Fathy, Mahmoud ^{[1
]}

Akitsu, Takashiro ^{[5
]}

Koketsu, Mamoru ^{[6
]}

Kellow, Ruba ^{[3
]}

Amigues, Eric ^{[3
]}

机构：

[1] Egyptian Petr Res Inst, PO 11727, Cairo, Egypt

[2] Univ Liverpool, Dept Chem, Liverpool L69 7ZD, Merseyside, England

[3] Xian Jiaotong Liverpool Univ, Dept Chem, Suzhou 215123, Jiangsu, Peoples R China

[4] Gazi Univ, Dept Chem, TR-06500 Ankara, Turkey

[5] Tokyo Univ Sci, Dept Chem, Fac Sci, Tokyo 1628601, Japan

[6] Gifu Univ, Dept Chem & Biomol Sci, Fac Engn, Gifu 5011193, Japan

来源：

RESEARCH ON CHEMICAL INTERMEDIATES | 2019年 / 45卷 / 03期

关键词：

3-Acetyl-4-hydroxyquinolin-2(1H)-one; Synthesis; Chemical reactivity; Condensation; Cyclization; Heterocycles; PHOTO-ANTIPROLIFERATIVE ACTIVITY; RING-CLOSURE REACTIONS; QUINOLINE DERIVATIVES; GLYCINE SITE; HETEROCYCLIZATION REACTIONS; ANTIMICROBIAL EVALUATION; STRUCTURAL DETERMINATION; POTENTIAL ANTIBACTERIAL; BIOLOGICAL EVALUATION; TAUTOMERIC STRUCTURE;

D O I：

10.1007/s11164-018-3652-1

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The chemistry of 3-acetyl-4-hydroxyquinolin-2(1H)-ones has attracted increased attention in both synthetic organic and medicinal chemistry, as numerous advancements in the use of this family of important compounds seems to be of considerable value. This account summarizes the results from the literature focusing on synthesis of 3-acetyl-4-hydroxyquinolin-2(1H)-ones as well as their reactions are also discussed.

引用

页码：919 / 934

页数：16

共 98 条

[11] Utility of 4-hydroxythiocoumarin in organic synthesis [J].