A Facile and Efficient Synthesis of Dihydroisobenzofuran Derivatives via Tandem Palladium-Catalyzed Coupling, Propargyl-Allenyl Rearrangement, [4+2] Cycloaddition and Aromatization Reaction

被引：30

作者：

Shen, Ruwei ^{[1
]}

Huang, Xian ^{[1
,2
]}

Chen, Lingzhu ^{[1
]}

机构：

[1] Zhejiang Univ, Dept Chem, Hangzhou 310028, Peoples R China

[2] Chinese Acad Sci, Shanghai Inst Organ Chem, State Key Lab Organomet Chem, Shanghai 200032, Peoples R China

来源：

ADVANCED SYNTHESIS & CATALYSIS | 2008年 / 350卷 / 18期

基金：

中国国家自然科学基金;

关键词：

allene intermediates; dihydroisobenzofuran derivatives; diversity-oriented synthesis; sequential reactions;

D O I：

10.1002/adsc.200800470

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

A variety of dihydroisobenzofuran derivatives has been prepared in good yields via an interesting sequential reaction consisting of palladium-catalyzed coupling, propargyl-allenyl rearrangement, [4+2] cycloaddition and aromatization. A double-coupling, rearrangement, [4+2] cycloaddltion and aromatization process is also described for the synthesis of more complex and diverse structures.

引用

页码：2865 / 2870

页数：6