Role of non-Genetic Risk Factors in Exacerbating Alcohol-related organ damage

被引:1
作者
Osna, Natalia A. [1 ,2 ]
Bhatia, Rakesh [3 ]
Thompson, Christopher [3 ]
Batra, Surinder K. [3 ]
Kumar, Sushil [3 ]
Cho, Yeonhee [4 ,5 ]
Szabo, Gyongyi [5 ]
Molina, Patricia E. [6 ]
Weinman, Steven A. [7 ,8 ]
Ganesan, Murali [1 ,2 ]
Kharbanda, Kusum K. [1 ,2 ,3 ]
机构
[1] Vet Affairs Nebraska Western Iowa Hlth Care Syst, Res Serv, Omaha, NE 68105 USA
[2] Univ Nebraska Med Ctr, Dept Internal Med, Omaha, NE USA
[3] Univ Nebraska Med Ctr, Dept Biochem & Mol Biol, Omaha, NE USA
[4] Univ Massachusetts, Sch Med, Dept Med, Worcester, MA USA
[5] Harvard Med Sch, Beth Israel Deaconess Med Ctr, Boston, MA 02115 USA
[6] LSUHSC New Orleans, Dept Physiol, New Orleans, LA USA
[7] Univ Kansas, Med Ctr, Dept Internal Med, Kansas City, KS 66103 USA
[8] Univ Kansas, Med Ctr, Liver Ctr, Kansas City, KS 66103 USA
基金
美国国家卫生研究院;
关键词
alcohol; infectious agents; HIV; HBV; smoking; neutrophil extracellular traps; ACETALDEHYDE-PROTEIN ADDUCTS; NEUTROPHIL EXTRACELLULAR TRAPS; INNATE IMMUNITY; HEPATITIS-C; LIVER-DISEASE; IN-VITRO; GUT; HIV; MALONDIALDEHYDE; CONSUMPTION;
D O I
10.1016/j.alcohol.2020.05.002
中图分类号
R194 [卫生标准、卫生检查、医药管理];
学科分类号
摘要
This review provides a summary of the symposium titled "Role of Non-Genetic Risk Factors in Exacerbating Alcohol-Related Organ Damage", which was held at the 42nd Annual Meeting of the Research Society on Alcoholism. The goals of the symposium were to provide newer insights into the role of nongenetic factors, including specific external factors, notably infectious agents or lifestyle factors, that synergistically act to exacerbate alcohol pathogenicity to generate more dramatic downstream biological defects. This summary of the symposium will benefit junior/senior basic scientists and clinicians currently investigating/treating alcohol-induced organ pathology, as well as undergraduate, graduate, and post-graduate students and fellows. Published by Elsevier Inc.
引用
收藏
页码:63 / 72
页数:10
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