Can Cancer Drugs Treat Immunodeficiency?

[1] Phosphoinositide 3-Kinase δ Gene Mutation Predisposes to Respiratory Infection and Airway Damage [J]. SCIENCE, 2013, 342 (6160) : 866 - 871

[2] A crucial role for the p110δ subunit of phosphatidylinositol 3-kinase in B cell development and activation [J]. JOURNAL OF EXPERIMENTAL MEDICINE, 2002, 196 (06) : 753 - 763

[3] Agammaglobulinemia and absent B lineage cells in a patient lacking the p85α subunit of PI3K [J]. JOURNAL OF EXPERIMENTAL MEDICINE, 2012, 209 (03) : 463 - 470

[4] Impaired B cell development and proliferation in absence of phosphoinositide 3-kinase p85α [J]. SCIENCE, 1999, 283 (5400) : 393 - 397

[5] PI3Kδ Inhibitors in Cancer: Rationale and Serendipity Merge in the Clinic [J]. CANCER DISCOVERY, 2011, 1 (07) : 562 - 572

[6] Essential, nonredundant role for the phosphoinositide 3-kinase p110δ in signaling by the B-cell receptor complex [J]. MOLECULAR AND CELLULAR BIOLOGY, 2002, 22 (24) : 8580 - 8591

[7] De novo somatic mutations in components of the PI3K-AKT3-mTOR pathway cause hemimegalencephaly [J]. NATURE GENETICS, 2012, 44 (08) : 941 - +

[8] Mosaic overgrowth with fibroadipose hyperplasia is caused by somatic activating mutations in PIK3CA [J]. NATURE GENETICS, 2012, 44 (08) : 928 - +

[9] Targeting the phosphoinositide 3-kinase pathway in cancer [J]. NATURE REVIEWS DRUG DISCOVERY, 2009, 8 (08) : 627 - 644

[10] Lucas C. L., 2013, NAT IMMUNOL, DOI [10.103/ni.2771, DOI 10.103/NI.2771]

[1] Phosphoinositide 3-Kinase δ Gene Mutation Predisposes to Respiratory Infection and Airway Damage [J]. SCIENCE, 2013, 342 (6160) : 866 - 871

[2] A crucial role for the p110δ subunit of phosphatidylinositol 3-kinase in B cell development and activation [J]. JOURNAL OF EXPERIMENTAL MEDICINE, 2002, 196 (06) : 753 - 763

[3] Agammaglobulinemia and absent B lineage cells in a patient lacking the p85α subunit of PI3K [J]. JOURNAL OF EXPERIMENTAL MEDICINE, 2012, 209 (03) : 463 - 470

[4] Impaired B cell development and proliferation in absence of phosphoinositide 3-kinase p85α [J]. SCIENCE, 1999, 283 (5400) : 393 - 397

[5] PI3Kδ Inhibitors in Cancer: Rationale and Serendipity Merge in the Clinic [J]. CANCER DISCOVERY, 2011, 1 (07) : 562 - 572

[6] Essential, nonredundant role for the phosphoinositide 3-kinase p110δ in signaling by the B-cell receptor complex [J]. MOLECULAR AND CELLULAR BIOLOGY, 2002, 22 (24) : 8580 - 8591

[7] De novo somatic mutations in components of the PI3K-AKT3-mTOR pathway cause hemimegalencephaly [J]. NATURE GENETICS, 2012, 44 (08) : 941 - +

[8] Mosaic overgrowth with fibroadipose hyperplasia is caused by somatic activating mutations in PIK3CA [J]. NATURE GENETICS, 2012, 44 (08) : 928 - +

[9] Targeting the phosphoinositide 3-kinase pathway in cancer [J]. NATURE REVIEWS DRUG DISCOVERY, 2009, 8 (08) : 627 - 644

[10] Lucas C. L., 2013, NAT IMMUNOL, DOI [10.103/ni.2771, DOI 10.103/NI.2771]