Antimicrobial Stewardship in the Neonatal Intensive Care Unit: An Update

被引:28
作者
Gkentzi, Despoina [1 ]
Dimitriou, Gabriel [1 ]
机构
[1] Patras Med Sch, Dept Paediat, Patras 26504, Greece
关键词
Antimicrobial stewardship; neonate; interventions; pathogens; Candida; therapeutic challenges; INFECTIOUS-DISEASES SOCIETY; VANCOMYCIN CONTINUOUS-INFUSION; EMPIRICAL ANTIBIOTIC-TREATMENT; GUIDED DECISION-MAKING; EARLY-ONSET SEPSIS; KLEBSIELLA-PNEUMONIAE; THERAPY; GUIDELINES; MANAGEMENT; RESTRICTION;
D O I
10.2174/1573396315666190118101953
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
Neonates represent a vulnerable population for infections and neonatal sepsis is a major cause of mortality and morbidity worldwide. Therefore, antimicrobials are the most commonly prescribed drugs in the Neonatal Intensive Care Unit Setting but unfortunately are quite often used inappropriately with various short and long-term effects. The rational use of antimicrobials is of paramount importance in this population and structured antimicrobial stewardship interventions should be in place. These interventions are slightly different from those used in adults and older children due to the particularities of the neonatal medicine. The aim of this review is to provide an update in the field and identify areas for further consideration and future research..
引用
收藏
页码:47 / 52
页数:6
相关论文
共 51 条
[31]  
Organization WH, 2014, Antimicrobial resistance
[32]   Australia-wide Point Prevalence Survey of Antimicrobial Prescribing in Neonatal Units How Much and How Good? [J].
Osowicki, Joshua ;
Gwee, Amanda ;
Noronha, Jesuina ;
Britton, Philip N. ;
Isaacs, David ;
Lai, Tony B. ;
Nourse, Clare ;
Avent, Minyon ;
Moriarty, Paul ;
Francis, Joshua R. ;
Blyth, Christopher C. ;
Cooper, Celia M. ;
Bryant, Penelope A. .
PEDIATRIC INFECTIOUS DISEASE JOURNAL, 2015, 34 (08) :E185-E190
[33]  
Pappas PG, 2016, CLIN INFECT DIS, V62, pE1, DOI 10.1093/cid/civ933
[34]   Infant antibiotic use and wheeze and asthma risk: a systematic review and meta-analysis [J].
Penders, J. ;
Kummeling, I. ;
Thijs, C. .
EUROPEAN RESPIRATORY JOURNAL, 2011, 38 (02) :295-302
[35]   The Conundrum of Early-Onset Sepsis [J].
Polin, Richard A. ;
Watterberg, Kristi ;
Benitz, William ;
Eichenwald, Eric .
PEDIATRICS, 2014, 133 (06) :1122-1123
[36]   Management of Neonates With Suspected or Proven Early-Onset Bacterial Sepsis [J].
Polin, Richard A. .
PEDIATRICS, 2012, 129 (05) :1006-1015
[37]  
Rybak Michael, 2009, Am J Health Syst Pharm, V66, P82, DOI [10.2146/ajhp080434, 10.1086/600877]
[38]   Risk factors for Candida species colonization of neonatal intensive care unit patients [J].
Saiman, L ;
Ludington, E ;
Dawson, JD ;
Patterson, JE ;
Rangel-Frausto, S ;
Wiblin, RT ;
Blumberg, HM ;
Pfaller, M ;
Rinaldi, M ;
Edwards, JE ;
Wenzel, RP ;
Jarvis, W .
PEDIATRIC INFECTIOUS DISEASE JOURNAL, 2001, 20 (12) :1119-1124
[39]   Volume of blood required to detect common neonatal pathogens [J].
Schelonka, RL ;
Chai, MK ;
Yoder, BA ;
Hensley, D ;
Brockett, RM ;
Ascher, DP .
JOURNAL OF PEDIATRICS, 1996, 129 (02) :275-278
[40]  
Shabaan AE, 2017, PEDIATR INFECT DIS J, V36, P358, DOI [10.1097/INF.0000000000001445, 10.1097/inf.0000000000001445]