Dielectric measurement of cell death

被引:112
作者
Patel, Pareshlumar [2 ]
Markx, Gerard H. [1 ]
机构
[1] Heriot Watt Univ, Dept Chem Engn, Microstruct & Microenvironm Res Grp, Sch Engn & Phys Sci, Edinburgh EH14 4AS, Midlothian, Scotland
[2] Univ Manchester, Sch Chem Engn & Analyt Sci, Manchester M60 1QD, Lancs, England
关键词
Capacitance; Permittivity; Dielectric spectroscopy; Dielectrophoresis; Electrorotation; Viability; Stress;
D O I
10.1016/j.enzmictec.2008.09.005
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
Dielectric techniques, which include dielectric spectroscopy as well as AC electrokinetic methods such as dielectrophoresis, electrorotation and electro-orientation. can be provide important information about cell viability. A review is given of the different dielectric techniques that have been used for measuring cell viability and their utility. The changes that occur in the cell dielectric properties during apoptotic and different forms of traumatic cell death are discussed and interpreted in terms of the main parameters involved (membrane capacitance and conductance and internal conductivity). (C) 2008 Elsevier Inc. All rights reserved.
引用
收藏
页码:463 / 470
页数:8
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