COVID-19: Understanding the science of antibody testing and lessons from the HIV epidemic

被引：4
作者：
Weiss, Stanley H. [1 ,2 ]
Wormser, Gary P. [3 ]
机构：
[1] Rutgers New Jersey Med Sch, Dept Med, Newark, NJ 07103 USA
[2] Rutgers Sch Publ Hlth, Dept Biostat & Epidemiol, Piscataway, NJ 08854 USA
[3] New York Med Coll, Dept Med, Div Infect Dis, Valhalla, NY 10595 USA
来源：
DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE | 2020年 / 98卷 / 01期
关键词：
SARS-CoV-2; Laboratory; Cross-reactivity; False positive; HIV; Antibody-dependent enhancement;
D O I：
10.1016/j.diagmicrobio.2020.115078
中图分类号：
R51 [传染病];
学科分类号：
100401 ;
摘要：
Potential pitfalls in the development, deployment and interpretation of antibody tests for COVID-19 are discussed. Lessons learned from the experience with the introduction of antibody tests for HIV are highlighted. Each test will need to be separately vetted for performance and clinical implementation based upon rigorous clinical trial data. The issues we highlight will also be similarly important for vaccine and therapeutic drug efficacy trials. (C) 2020 Elsevier Inc. All rights reserved.
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页数：3
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