Overview of expression of matrix metalloproteinases (MMP-17, MMP-18, and MMP-20) in cultured human cells

被引：55

作者：

Grant, GM ^{[1
]}

Giambernardi, TA ^{[1
]}

Grant, AM ^{[1
]}

Klebe, RJ ^{[1
]}

机构：

[1] Univ Texas, Hlth Sci Ctr, Dept Cellular & Struct Biol, San Antonio, TX 78284 USA

来源：

MATRIX BIOLOGY | 1999年 / 18卷 / 02期

关键词：

matrix metalloproteinase; membrane-type metalloproteinase-4; enamelysin; collagenase;

D O I：

10.1016/S0945-053X(99)00003-7

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

We recently described the cell type distribution of several matrix metalloproteinases (MMP-1 through MMP-16). In this report we extend this study by analysis of three recently described MMPs. PCR primers for MMP-17, MMP-18, and MMP-20 were optimized for use in RT-PCR. The results demonstrate one or more cell lines or tissue that express mRNA for each of these newly described MMPs. (C) 1999 Elsevier Science B.V./International Society of Matrix Biology. All rights reserved.

引用

页码：145 / 148

页数：4

共 10 条

[1] The matrix metalloproteinase-14 (MMP-14) gene is structurally distinct from other MMP genes and is co-expressed with the TIMP-2 gene during mouse embryogenesis [J].

Apte, SS ;

Fukai, N ;

Beier, DR ;

Olsen, BR .

JOURNAL OF BIOLOGICAL CHEMISTRY, 1997, 272 (41) :25511-25517

[2] Molecular cloning and mRNA tissue distribution of a novel matrix metalloproteinase isolated from porcine enamel organ [J].

Bartlett, JD ;

Simmer, JP ;

Xue, J ;

Margolis, HC ;

Moreno, EC .

GENE, 1996, 183 (1-2) :123-128

[3] PROTEOLYTIC REMODELING OF EXTRACELLULAR-MATRIX [J].

BIRKEDALHANSEN, H .

CURRENT OPINION IN CELL BIOLOGY, 1995, 7 (05) :728-735

[4] SOME PRACTICAL CONSIDERATIONS AND APPLICATIONS OF THE NATIONAL-CANCER-INSTITUTE IN-VITRO ANTICANCER DRUG DISCOVERY SCREEN [J].

BOYD, MR ;

PAULI, KD .

DRUG DEVELOPMENT RESEARCH, 1995, 34 (02) :91-109

[5] Identification of MMP-18, a putative novel human matrix metalloproteinase [J].

Cossins, J ;

Dudgeon, TJ ;

Catlin, G ;

Gearing, AJH ;

Clements, JM .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1996, 228 (02) :494-498

[6] Overview of matrix metalloproteinase expression in cultured human cells [J].

Giambernardi, TA ;

Grant, GM ;

Taylor, GP ;

Hay, RJ ;

Maher, VM ;

McCormick, JJ ;

Klebe, RJ .

MATRIX BIOLOGY, 1998, 16 (08) :483-496

[7] Identification and structural and functional characterization of human enamelysin (MMP-20) [J].

Llano, E ;

Pendas, AM ;

Knauper, V ;

Sorsa, T ;

Salo, T ;

Salido, E ;

Murphy, G ;

Simmer, JP ;

Bartlett, JD ;

LopezOtin, C .

BIOCHEMISTRY, 1997, 36 (49) :15101-15108

[8] Identification and characterization of a novel human matrix metalloproteinase with unique structural characteristics, chromosomal location, and tissue distribution [J].

Pendas, AM ;

Knauper, V ;

Puente, XS ;

Llano, E ;

Mattei, MG ;

Apte, S ;

Murphy, G ;

LopezOtin, C .

JOURNAL OF BIOLOGICAL CHEMISTRY, 1997, 272 (07) :4281-4286

[9]

Puente XS, 1996, CANCER RES, V56, P944

[10]

Sato H, 1996, J BIOCHEM-TOKYO, V119, P209

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