Utility of Antimullerian Hormone Level Obtained for Infertility Assessment for Alerting to Ovarian Tumor

被引：0
作者：
Hill, Bryan J.
Morrell, Travis J.
Zhang, Mallory M.
Norian, John M.
机构：
[1] Loma Linda Univ, Sch Med, Dept Gynecol & Obstet, Loma Linda, CA USA
[2] Loma Linda Univ, Sch Med, Dept Family Med, Loma Linda, CA USA
[3] Loma Linda Univ, Sch Med, Sect Reprod Endocrinol & Infertil, Loma Linda, CA USA
[4] Kaiser Permanente Fontana Med Ctr, Div Gynecol Oncol, Dept Obstet & Gynecol, Fontana, CA USA
来源：
OBSTETRICS AND GYNECOLOGY | 2013年 / 121卷 / 02期
关键词：
ANTI-MULLERIAN HORMONE; GRANULOSA-CELL TUMORS; AMH;
D O I：
10.1097/AOG.0b013e31827d8ff3
中图分类号：
R71 [妇产科学];
学科分类号：
100211 ;
摘要：
BACKGROUND: Antimullerian hormone is a marker of ovarian reserve and is now routinely measured in women seeking infertility treatment. CASE: A 42-year-old woman, gravida 1, abortus 1, presented with secondary infertility. Obtained originally for assessment of ovarian reserve, an antimullerian hormone of more than 160 ng/mL raised suspicion for a granulosa cell tumor. A laparoscopic right salpingo-oophorectomy, pelvic washings, dilation and curettage, and peritoneal and omental biopsies were performed. A well-differentiated granulosa cell tumor confined to the right ovary was consistent with stage 1A disease. CONCLUSION: As the use of antimullerian hormone becomes more common for ovarian reserve testing, providers need to maintain an awareness for neoplastic disease with abnormal values.
引用
收藏
页码：454 / 457
页数：5
相关论文
共 8 条
[1]   Serum Mullerian Inhibiting Substance/Anti-Mullerian Hormone levels in patients with adult granulosa cell tumors directly correlate with aggregate tumor mass as determined by pathology or radiology [J].
Chang, Henry L. ;
Pahlavan, Nima ;
Halpern, Elkan F. ;
MacLaughlin, David T. .
GYNECOLOGIC ONCOLOGY, 2009, 114 (01) :57-60
[2]   Ovarian granulosa cell tumors express a functional membrane receptor for anti-Mullerian hormone in transgenic mice [J].
Dutertre, M ;
Gouédard, L ;
Xavier, F ;
Long, WQ ;
di Clemente, N ;
Picard, JY ;
Rey, R .
ENDOCRINOLOGY, 2001, 142 (09) :4040-4046
[3]   Anti-Mullerian hormone and its role in ovarian function [J].
Gruijters, MJG ;
Visser, JA ;
Durlinger, ALL ;
Themmen, APN .
MOLECULAR AND CELLULAR ENDOCRINOLOGY, 2003, 211 (1-2) :85-90
[4]   Anti-Mullerian hormone (AMH) as a predictive marker in assisted reproductive technology (ART) [J].
La Marca, A. ;
Sighinolfi, G. ;
Radi, D. ;
Argento, C. ;
Baraldi, E. ;
Artenisio, A. Carducci ;
Stabile, G. ;
Volpe, A. .
HUMAN REPRODUCTION UPDATE, 2010, 16 (02) :113-130
[5]   The Anti-Mullerian hormone and ovarian cancer [J].
La Marca, Antonio ;
Volpe, Annibale .
HUMAN REPRODUCTION UPDATE, 2007, 13 (03) :265-273
[6]   Granulosa cell tumors of the ovary: The clinical value of serum inhibin A and B levels in a large single center cohort [J].
Mom, C. H. ;
Engelen, M. J. A. ;
Willemse, P. H. B. ;
Gietema, J. A. ;
ten Hoor, K. A. ;
de Vries, E. G. E. ;
van der Zee, A. G. J. .
GYNECOLOGIC ONCOLOGY, 2007, 105 (02) :365-372
[7]   The relationships between AMH, androgens, insulin resistance and basal ovarian follicular status in non-obese subfertile women with and without polycystic ovary syndrome [J].
Nardo, Luciano G. ;
Yates, Allen P. ;
Roberts, Stephen A. ;
Pemberton, Phil ;
Laing, Ian .
HUMAN REPRODUCTION, 2009, 24 (11) :2917-2923
[8]   Granulosa cell tumor of the ovary [J].
Schumer, ST ;
Cannistra, SA .
JOURNAL OF CLINICAL ONCOLOGY, 2003, 21 (06) :1180-1189
1