Asplenia and functional hyposplenism in autoimmune polyglandular syndrome type 1

被引:9
|
作者
Pollak, Uri [1 ]
Bar-Sever, Zvi [3 ]
Hoffer, Vered [1 ]
Marcus, Nufar [1 ,2 ]
Scheuerman, Oded [1 ]
Garty, Ben Zion [1 ,2 ]
机构
[1] Schneider Childrens Med Ctr Israel, Dept Pediat B, IL-49202 Petah Tiqwa, Israel
[2] Schneider Childrens Med Ctr Israel Petah Tiqwa, Kipper Inst Allergy & Imunol, Tel Aviv, Israel
[3] Tel Aviv Univ, Sackler Fac Med, Div Nucl Med, IL-69978 Tel Aviv, Israel
关键词
Asplenia; Autoimmune polyglandular syndrome; DISEASE TYPE-I; CANDIDIASIS; EXPRESSION;
D O I
10.1007/s00431-008-0735-9
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
Asplenia was diagnosed in four patients with autoimmune polyendocrine syndrome type-I (APS-I): two children, aged 2-4 years, from the same family and two adults, the father of the two children and his cousin. We have observed a worsening in splenic function in the children during a follow-up of a few years. Patients with APS-I should be evaluated for splenic function, since splenic dysfunction has important therapeutic implications, especially in children.
引用
收藏
页码:233 / 235
页数:3
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