Strategies to manage hepatitis C virus infection disease burden - volume 3

被引：33

作者：

Alfaleh, F. Z. ^{[1
]}

Nugrahini, N. ^{[2
]}

Maticic, M. ^{[3
]}

Tolmane, I. ^{[4
,5
]}

Alzaabi, M. ^{[6
]}

Hajarizadeh, B. ^{[7
,8
]}

Valantinas, J. ^{[9
]}

Kim, D. Y. ^{[10
]}

Hunyady, B. ^{[11
,12
]}

Abaalkhail, F. ^{[13
]}

Abbas, Z. ^{[14
]}

Abdou, A. ^{[15
]}

Abourached, A. ^{[16
]}

Al Braiki, F. ^{[17
]}

Al Hosani, F. ^{[18
]}

Al Jaberi, K. ^{[19
]}

Al Khatry, M. ^{[20
]}

Al Mulla, M. A. ^{[18
]}

Al Quraishi, H. ^{[21
]}

Al Rifai, A. ^{[22
]}

Al Serkal, Y. ^{[23
]}

Alam, A. ^{[24
]}

Alashgar, H. I. ^{[25
]}

Alavian, S. M. ^{[26
,27
]}

Alawadhi, S. ^{[15
]}

Al-Dabal, L. ^{[28
]}

Aldins, P. ^{[29
]}

Alghamdi, A. S. ^{[30
]}

Al-Hakeem, R. ^{[31
]}

Aljumah, A. A. ^{[32
,33
]}

Almessabi, A. ^{[17
]}

Alqutub, A. N. ^{[30
]}

Alswat, K. A. ^{[34
]}

Altraif, I. ^{[32
,33
]}

Andrea, N. ^{[35
]}

Assiri, A. M. ^{[31
]}

Babatin, M. A. ^{[30
]}

Baqir, A. ^{[36
]}

Barakat, M. T. ^{[37
]}

Bergmann, O. M. ^{[38
]}

Bizri, A. R. ^{[39
]}

Chaudhry, A. ^{[40
]}

Choi, M. S. ^{[41
]}

Diab, T. ^{[42
]}

Djauzi, S. ^{[43
]}

El Hassan, E. S. ^{[15
]}

El Khoury, S. ^{[44
]}

Estes, C. ^{[45
]}

Fakhry, S. ^{[46
]}

Farooqi, J. I. ^{[47
,48
]}

机构：

[1] King Saud Univ, Liver Dis Res Ctr, Riyadh, Saudi Arabia

[2] Minist Hlth, Directorate Direct Transmitted Dis Control Dis Co, Sub Directorate Gastrointestinal Infect Diarrheal, Jakarta, Indonesia

[3] Univ Med Ctr, Clin Infect Dis & Febrile Illnesses, Ljubljana, Slovenia

[4] Infectol Ctr Latvia, Dept Hepatol, Riga, Latvia

[5] Riga Stradins Univ, Dept Infectol & Dermatol, Riga, Latvia

[6] Zayed Mil Hosp, Abu Dhabi, U Arab Emirates

[7] Univ New S Wales, Kirby Inst, Sydney, NSW, Australia

[8] La Trobe Univ, Australian Res Ctr Sex Hlth & Soc, Melbourne, Vic, Australia

[9] Vilnius State Univ, Fac Med, Ctr Hepatol Gastroenterol & Dietet, Vilnius, Lithuania

[10] Yonsei Univ, Coll Med, Dept Internal Med, Seoul, South Korea

[11] Somogy Cty Kaposi Mor Teaching Hosp, Dept Gastroenterol, Kaposvar, Hungary

[12] Univ Pecs, Dept Med 1, Pecs, Hungary

[13] Alfaisal Univ, King Faisal Specialist Hosp & Res Ctr, Dept Liver & Small Bowel Transplantat, Riyadh, Saudi Arabia

[14] Ziauddin Univ, Karachi, Pakistan

[15] Rashid Hosp, Dubai Hlth Author, Dubai, U Arab Emirates

[16] Minist Publ Hlth, Natl Hepatitis Program, Beirut, Lebanon

[17] Abu Dhabi Hlth Serv Co, Abu Dhabi, U Arab Emirates

[18] Hlth Author Abu Dhabi, Communicable Dis Dept, Abu Dhabi, U Arab Emirates

[19] Hlth Author Abu Dhabi, Hlth Regulat Div, Abu Dhabi, U Arab Emirates

[20] Ras Al Khaimah Hosp, Ras Al Khaymah, U Arab Emirates

[21] Dubai Hlth Author, Dubai, U Arab Emirates

[22] Mafraq Hosp, Abu Dhabi, U Arab Emirates

[23] Minist Hlth, Hosp Sect, Al Ain, U Arab Emirates

[24] Shaikh Zayed Hosp, Lahore, Pakistan

[25] King Faisal Specialist Hosp & Res Ctr, Dept Med, Riyadh 11211, Saudi Arabia

[26] Baqiatallah Univ Med Sci, Baqiatallah Res Ctr Gastroenterol & Liver Dis, Tehran, Iran

[27] Middle East Liver Dis Ctr, Tehran, Iran

[28] Rashid Hosp, Dubai Hlth Author, Dept Pulm Med, Dubai, U Arab Emirates

[29] Pauls Stradins Clin Univ Hosp, Infect Control Dept, Riga, Latvia

[30] King Fahad Hosp, Dept Med Specialties, Gastroenterol & Hepatol Unit, Riyadh, Saudi Arabia

[31] Minist Hlth, Dept Prevent Med, Riyadh, Saudi Arabia

[32] King Abdul Aziz Med City, Riyadh, Saudi Arabia

[33] King Saud bin Abdulaziz Univ Hlth Sci, Riyadh, Saudi Arabia

[34] King Saud Univ, Coll Med, Dept Med, Liver Dis Res Ctr, Riyadh 11461, Saudi Arabia

[35] Daman Natl Hlth Insurance Co, Abu Dhabi, U Arab Emirates

[36] Seyal Med Ctr, Multan, Pakistan

[37] Hlth Author Abu Dhabi, Abu Dhabi, U Arab Emirates

[38] Landspitali, Div Gastroenterol & Hepatol, Reykjavik, Iceland

[39] Amer Univ Beirut, Med Ctr, Fac Med, Div Infect Dis, Beirut, Lebanon

[40] Siddiq Sadiq Hosp, Gujranwala Liver Fdn, Gujranwala, Pakistan

[41] Sungkyunkwan Univ, Sch Med, Samsung Med Ctr, Dept Med, Seoul, South Korea

[42] Al Ain Hosp, Al Ain, U Arab Emirates

[43] Univ Indonesia, Dr Cipto Mangunkusumo Hosp, Fac Med, Div Hepatobiliary,Dept Internal Med, Jakarta, Indonesia

[44] Univ Balamand, St George Hosp, Dept Gastroenterol, El Koura, Lebanon

[45] Ctr Dis Anal, Louisville, CO 80026 USA

[46] Abu Dhabi Police, Abu Dhabi, U Arab Emirates

[47] Khyber Med Univ, Postgrad Med Inst, Peshawar, Pakistan

[48] Govt Lady Reading Hosp, Peshawar, Pakistan

[49] Landspitali, Reykjavik, Iceland

[50] Lady Reading Hosp, Dept Gastroenterol & Hepatol, Peshawar, Pakistan

来源：

JOURNAL OF VIRAL HEPATITIS | 2015年 / 22卷

关键词：

diagnosis; disease burden; elimination; epidemiology; hepatitis C; hepatitis C virus; incidence; mortality; prevalence; scenarios; strategy; treatment; TODAYS TREATMENT PARADIGM; HEPATOCELLULAR-CARCINOMA; HCV; EPIDEMIOLOGY; POPULATION; PREVALENCE; INCREASE; RISK;

D O I：

10.1111/jvh.12474

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

The hepatitis C virus (HCV) epidemic was forecasted through 2030 for 15 countries in Europe, the Middle East and Asia, and the relative impact of two scenarios was considered: increased treatment efficacy while holding the annual number of treated patients constant and increased treatment efficacy and an increased annual number of treated patients. Increasing levels of diagnosis and treatment, in combination with improved treatment efficacy, were critical for achieving substantial reductions in disease burden. A 90% reduction in total HCV infections within 15years is feasible in most countries studied, but it required a coordinated effort to introduce harm reduction programmes to reduce new infections, screening to identify those already infected and treatment with high cure rate therapies. This suggests that increased capacity for screening and treatment will be critical in many countries. Birth cohort screening is a helpful tool for maximizing resources. Among European countries, the majority of patients were born between 1940 and 1985. A wider range of birth cohorts was seen in the Middle East and Asia (between 1925 and 1995).

引用

页码：42 / 65

页数：24

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