Literature review on the role of dietary protein and amino acids in cognitive functioning and cognitive decline

被引：60
作者：
van de Rest, Ondine [1 ]
van der Zwaluw, Nikita L. [1 ]
de Groot, Lisette C. P. G. M. [1 ]
机构：
[1] Wageningen Univ, Div Human Nutr, NL-6700 EV Wageningen, Netherlands
来源：
AMINO ACIDS | 2013年 / 45卷 / 05期
关键词：
Dietary protein; Amino acids; Tyrosine; Tryptophan; Dementia; Cognitive functioning; Cognitive decline; ALPHA-LACTALBUMIN INCREASES; NUTRITIONAL-STATUS; WORKING-MEMORY; L-TRYPTOPHAN; ALZHEIMERS-DISEASE; PLASMA TRYPTOPHAN; ELDERLY-PEOPLE; SLEEP-DEPRIVATION; MOTOR-PERFORMANCE; CARBOHYDRATE-RICH;
D O I：
10.1007/s00726-013-1583-0
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
As the population of elderly people is growing rapidly, the number of individuals with dementia and cognitive impairment is also increasing. One of the preventive measures against cognitive decline is diet and different dietary factors have already been investigated. This review provides an overview of studies on dietary protein and cognitive functioning and cognitive decline. Also studies on the individual amino acids that are related to brain function, tryptophan and tyrosine, are discussed. Overall, the role of dietary protein intake on cognitive functioning as well as cognitive decline has hardly been studied; we found eight observational studies and three intervention studies. More studies investigated the role of tryptophan (14 studies) and tyrosine (nine studies) in relation to cognitive functioning, but all these studies were performed in young adult populations and mostly under special conditions. Research in elderly populations, in particular, is warranted. Also more research is needed to come to definitive conclusions and specific recommendations regarding protein intake or intake of specific amino acids for maintaining optimal cognitive functioning.
引用
收藏
页码：1035 / 1045
页数：11
相关论文
共 60 条
  • [1] [Anonymous], 2012, DEM PUBL HLTH PRIOR
  • [2] ARNSTEN AFT, 1995, J NEUROSCI, V15, P3429
  • [3] ASHCROFT GW, 1965, J NEUROCHEM, V12, P483, DOI 10.1111/j.1471-4159.1965.tb06775.x
  • [4] PHYSICAL FRAILTY PREDICTS FUTURE COGNITIVE DECLINE - A FOUR-YEAR PROSPECTIVE STUDY IN 2737 COGNITIVELY NORMAL OLDER ADULTS
    Auyeung, T. W.
    Lee, J. S. W.
    Kwok, T.
    Woo, J.
    [J]. JOURNAL OF NUTRITION HEALTH & AGING, 2011, 15 (08) : 690 - 694
  • [5] The correlative triad among aging, dopamine, and cognition:: Current status and future prospects
    Backman, Lars
    Nyberg, Lars
    Lindenberger, Ulman
    Li, Shu-Chen
    Farde, Lars
    [J]. NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS, 2006, 30 (06) : 791 - 807
  • [6] TREATMENT WITH TYROSINE, A NEUROTRANSMITTER PRECURSOR, REDUCES ENVIRONMENTAL-STRESS IN HUMANS
    BANDERET, LE
    LIEBERMAN, HR
    [J]. BRAIN RESEARCH BULLETIN, 1989, 22 (04) : 759 - 762
  • [7] Protein Intake and Incident Frailty in the Women's Health Initiative Observational Study
    Beasley, Jeannette M.
    LaCroix, Andrea Z.
    Neuhouser, Marian L.
    Huang, Ying
    Tinker, Lesley
    Woods, Nancy
    Michael, Yvonne
    Curb, J. David
    Prentice, Ross L.
    [J]. JOURNAL OF THE AMERICAN GERIATRICS SOCIETY, 2010, 58 (06) : 1063 - 1071
  • [8] Diet rich in α-lactalbumin improves memory in unmedicated recovered depressed patients and matched controls
    Booij, Linda
    Merens, Wendelien
    Markus, C. Rob
    Van der Does, A. J. Willem
    [J]. JOURNAL OF PSYCHOPHARMACOLOGY, 2006, 20 (04) : 526 - 535
  • [9] Frailty is associated with incident Alzheimer's disease and cognitive decline in the elderly
    Buchman, Aron S.
    Boyle, Patricia A.
    Wilson, Robert S.
    Tang, Yuxiao
    Bennett, David A.
    [J]. PSYCHOSOMATIC MEDICINE, 2007, 69 (05): : 483 - 489
  • [10] Fitness effects on the cognitive function of older adults: A meta-analytic study
    Colcombe, S
    Kramer, AF
    [J]. PSYCHOLOGICAL SCIENCE, 2003, 14 (02) : 125 - 130
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