Heart valve engineering: decellularized allograft matrices in clinical practice

被引：27
|
作者：
Neumann, Anneke [1 ]
Cebotari, Serghei [1 ]
Tudorache, Igor [1 ]
Haverich, Axel [1 ]
Sarikouch, Samir [1 ]
机构：
[1] Hannover Med Sch, Dept Cardiothorac Transplantat & Vasc Surg, D-30625 Hannover, Germany
来源：
BIOMEDICAL ENGINEERING-BIOMEDIZINISCHE TECHNIK | 2013年 / 58卷 / 05期
关键词：
allogenic; artificial; heart valve replacement; matrices; scaffolds; tissue engineering; STANDARD CRYOPRESERVED ALLOGRAFTS; VENTRICULAR OUTFLOW TRACT; MEAN FOLLOW-UP; PULMONARY VALVE; PEDIATRIC-PATIENTS; AORTIC HOMOGRAFT; ROSS OPERATION; EARLY FAILURE; IMPLANTATION; PORCINE;
D O I：
10.1515/bmt-2012-0115
中图分类号：
R318 [生物医学工程];
学科分类号：
0831 ;
摘要：
The purpose of this review is to update the current clinical experience with tissue-engineered, non-seeded, allogenic matrices for pulmonary and aortic valve replacement. Allogenic heart valve replacement using an aortic root homograft was first performed 50 years ago on July 24, 1962, by Donald Ross at Guy's Hospital, London. Cryopreserved homografts have been the gold standard for many years in selected indications such as for pulmonary valve replacement in congenital heart disease, severe bacterial endocarditis, or for right ventricular outflow tract reconstruction during the Ross pulmonary autograft operation. However, there is evolving evidence that tissue-engineered decellularized homografts may be superior to conventional cryopreserved homografts.
引用
收藏
页码：453 / 456
页数：4
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