Simultaneous viscosity and elasticity measurement using laser speckle contrast imaging

被引:12
作者
Chen, Xiao [1 ,2 ]
Wang, Yang [1 ,2 ]
Lu, Jinling [1 ,2 ]
Li, Pengcheng [1 ,2 ,3 ]
机构
[1] Huazhong Univ Sci & Technol, Wuhan Natl Lab Optoelect, Britton Chance Ctr Biomed Photon, Wuhan 430074, Hubei, Peoples R China
[2] Huazhong Univ Sci & Technol, Dept Biomed Engn, Minist Educ, Key Lab Biomed Photon, Wuhan 430074, Hubei, Peoples R China
[3] HUST Suzhou Inst Brainsmat, Suzhou 215125, Peoples R China
基金
中国国家自然科学基金;
关键词
OPTICAL COHERENCE TOMOGRAPHY; ULTRASOUND RADIATION FORCE; GELATIN PHANTOMS; SURFACE-WAVES; SHEAR-WAVES; ELASTOGRAPHY; VISCOELASTICITY; SKIN;
D O I
10.1364/OL.43.001582
中图分类号
O43 [光学];
学科分类号
070207 ; 0803 ;
摘要
Viscosity and elasticity are closely related to the physiological characteristics of biological tissues. This Letter reports a simultaneous quantitative measurement of these parameters realized with the laser speckle contrast imaging method. The propagation of a Rayleigh wave induced by an acoustic speaker is traced, and the frequency-dependent velocity dispersion is extracted with the frequency wavenumber spectrum analysis method. The viscosity and elasticity moduli of oil-in-gelatin tissue-mimicking phantoms are calculated by fitting the dispersion curves to the Voigt model. The method is validated by comparing it with the results obtained by using a conventional mechanical rheometer. (c) 2018 Optical Society of America
引用
收藏
页码:1582 / 1585
页数:4
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