In vitro allergy testing

被引:0
|
作者
Ott, H. [1 ]
Baron, I. [1 ]
Merk, H. F. [1 ]
机构
[1] Univ Aachen, Klin Dermatol & Allergol, Hautklin, D-52074 Aachen, Germany
来源
HAUTARZT | 2006年 / 57卷 / 06期
关键词
immunoglobulin E; basophil activation test; allergen microarray; lymphocyte transformation test; immunoblot;
D O I
10.1007/s00105-006-1167-y
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Along with the history, skin tests and provocation tests, in vitro test procedures are essential for the adequate care for patients with allergies. While serological investigations of immediate-type allergic reactions primarily detect allergen-specific IgE antibodies, basophil activation tests with different read-out parameters are available for cellular diagnosis of immediate-type reaction patterns. If clinically necessary, further immunological methods (i.e. immunoblots, lymphocyte transformation tests) can be employed. New options are provided by allergen microarray technology, which makes it possible to determine not only the specific antigenic protein but also to analyze different epitopes.
引用
收藏
页码:502 / +
页数:6
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