Formal anti-Markovnikov Hydroamination of Terminal Aryl Alkynes with Pinacolborane and Hydroxylamines via Zr/Cu Sequential Catalysis

被引：21
|
作者：
Sakae, Ryosuke [1 ]
Hirano, Koji [1 ]
Satoh, Tetsuya [1 ]
Miura, Masahiro [1 ]
机构：
[1] Osaka Univ, Fac Engn, Dept Appl Chem, Suita, Osaka 5650871, Japan
来源：
CHEMISTRY LETTERS | 2013年 / 42卷 / 10期
关键词：
ELECTROPHILIC AMINATION APPROACH; SECONDARY-AMINES; ARYLBORONIC ACIDS; ALKENES; CHLOROAMINES; DERIVATIVES; ACETALS;
D O I：
10.1246/cl.130485
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
We have developed sequential Zr/Cu catalysis involving regioselective hydroboration and electrophilic amination for the formal anti-Markovnikov hydroamination of terminal aryl alkynes. The reaction system can provide a facile access to enamines from terminal acetylenes with high regioselectivity under mild conditions.
引用
收藏
页码：1128 / 1130
页数：3
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