Protein kinase C isoform expression in chronic lymphocytic leukemia: a potential target for therapy?

被引：3
作者：
Best, O. Giles [1 ]
Tam, Constantine [2 ,3 ]
机构：
[1] Royal N Shore Hosp, Kolling Inst Med Res, Northern Blood Res Ctr, Sydney, NSW 2065, Australia
[2] St Vincents Hosp, Dept Haematol, Fitzroy, Vic 3065, Australia
[3] Univ Melbourne, Parkville, Vic 3052, Australia
来源：
LEUKEMIA & LYMPHOMA | 2013年 / 54卷 / 10期
关键词：
B-CLL; BETA-II; CELLS; APOPTOSIS; SURVIVAL; PKC; MECHANISMS;
D O I：
10.3109/10428194.2013.779692
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
引用
收藏
页码：2098 / 2099
页数：2
相关论文
共 19 条
[1]   B-cell receptor signaling in chronic lymphocytic leukemia cells is regulated by overexpressed active protein kinase CβII [J].
Abrams, Simon T. ;
Lakum, Tasneem ;
Lin, Ke ;
Jones, Gemma M. ;
Treweeke, Andrew T. ;
Farahani, Mosavar ;
Hughes, Mair ;
Zuzel, Mirko ;
Slupsky, Joseph R. .
BLOOD, 2007, 109 (03) :1193-1201
[2]   Survival role of protein kinase C (PKC) in chronic lymphocytic leukemia and determination of isoform expression pattern and genes altered by PKC inhibition [J].
Alkan, S ;
Huang, O ;
Ergin, M ;
Denning, MF ;
Nand, S ;
Maududi, T ;
Paner, GP ;
Ozpuyan, F ;
Izban, KF .
AMERICAN JOURNAL OF HEMATOLOGY, 2005, 79 (02) :97-106
[3]   Regulation of Akt/PKB by phosphatidylinositol 3-kinase-dependent and -independent pathways in B-cell chronic lymphocytic leukemia cells:: role of protein kinase Cβ [J].
Barragan, Montserrat ;
de Frias, Merce ;
Iglesias-Serret, Daniel ;
Campas, Clara ;
Castano, Esther ;
Santidrian, Antonio F. ;
Coll-Mulet, Llorenc ;
Cosialls, Ana M. ;
Domingo, Alicia ;
Pons, Gabriel ;
Gil, Joan .
JOURNAL OF LEUKOCYTE BIOLOGY, 2006, 80 (06) :1473-1479
[4]  
Burger JA, 2010, BLOOD S1, V116
[5]   UCN-01 induces cytotoxicity toward human CLL cells through a p53-independent mechanism [J].
Byrd, JC ;
Shinn, C ;
Willis, CR ;
Flinn, IW ;
Lehman, T ;
Suasville, E ;
Lucas, D ;
Gerver, MR .
EXPERIMENTAL HEMATOLOGY, 2001, 29 (06) :703-708
[6]  
Forsyth CJ, 2009, BLOOD S1, V114
[7]  
Furman RR, 2010, BLOOD S1, V116
[8]  
Ganeshaguru K, 2002, HAEMATOLOGICA, V87, P167
[9]   NOTCH2 links protein kinase C delta to the expression of CD23 in chronic lymphocytic leukaemia (CLL) cells [J].
Hubmann, Rainer ;
Duechler, Markus ;
Schnabl, Susanne ;
Hilgarth, Martin ;
Demirtas, Dita ;
Mitteregger, Dieter ;
Hoelbl, Andrea ;
Vanura, Katrina ;
Le, Trang ;
Look, Thomas ;
Schwarzmeier, Josef D. ;
Valent, Peter ;
Jaeger, Ulrich ;
Shehata, Medhat .
BRITISH JOURNAL OF HAEMATOLOGY, 2010, 148 (06) :868-878
[10]   Protein kinase C expression is deregulated in chronic lymphocytic leukemia [J].
Kabir, Nuzhat N. ;
Ronnstrand, Lars ;
Kazi, Julhash U. .
LEUKEMIA & LYMPHOMA, 2013, 54 (10) :2288-2290
12