共 50 条
- [41] Mutant ASXL1 induces age-related expansion of phenotypic hematopoietic stem cells through activation of Akt/mTOR pathwayNATURE COMMUNICATIONS, 2021, 12 (01)Fujino, TakeshiGoyama, SusumuSugiura, YukiInoue, DaichiAsada, ShuheiYamasaki, SatoshiMatsumoto, AkikoYamaguchi, KiyoshiIsobe, YumikoTsuchiya, AkihoShikata, ShioriSato, NaruMorinaga, HironobuFukuyama, TomofusaTanaka, YosukeFukushima, TsuyoshiTakeda, ReinaYamamoto, KeitaHonda, HiroakiNishimura, Emi K.Furukawa, YoichiShibata, TatsuhiroAbdel-Wahab, OmarSuematsu, MakotoKitamura, Toshio
- [42] Clonal hematopoiesis-related mutant ASXL1 promotes atherosclerosis in mice via dysregulated innate immunityNATURE CARDIOVASCULAR RESEARCH, 2024, 3 (12): : 1568 - 1583Sato, NaruGoyama, SusumuChang, Yu-HsuanMiyawaki, MasashiFujino, TakeshiKoide, ShuheiDenda, TamamiLiu, XiaoxiaoUeda, KojiYamamoto, KeitaAsada, ShuheiTakeda, ReinaYonezawa, TaishiTanaka, YosukeHonda, HiroakiOta, YasunoriShibata, TakumaSekiya, MotohiroIsobe, TomoyaLamagna, ChrystelleMasuda, EstebanIwama, AtsushiShimano, HitoshiInoue, Jun-ichiroMiyake, KensukeKitamura, Toshio
- [43] Pathogenic ASXL1 somatic variants in reference databases complicate germline variant interpretation for Bohring-Opitz SyndromeHUMAN MUTATION, 2017, 38 (05) : 517 - 523Carlston, Colleen M.O'Donnell-Luria, Anne H.Underhill, Hunter R.Cummings, Beryl B.Weisburd, BenMinikel, Eric V.Birnbaum, Daniel P.Tvrdik, TatianaMacArthur, Daniel G.Mao, Rong
- [44] Targeting lysine demethylase 6B ameliorates ASXL1 truncation-mediated myeloid malignancies in modelsJOURNAL OF CLINICAL INVESTIGATION, 2024, 134 (01):Ge, GuoZhang, PengSui, PinpinChen, ShiYang, HuiGuo, YingRubalcava, Ivan P.Noor, AsraDelma, Caroline R.Agosto-Pena, JoelGeng, HuiMedina, Edward A.Liang, YingNimer, Stephen D.Mesa, RubenAbdel-Wahab, OmarXu, MingjiangYang, Feng-Chun
- [45] RUNX1 mutations promote leukemogenesis of myeloid malignancies in ASXL1-mutated leukemiaJOURNAL OF HEMATOLOGY & ONCOLOGY, 2019, 12 (01)Bera, RabindranathChiu, Ming-ChunHuang, Ying-JungLin, Tung-HueiKuo, Ming-ChungShih, Lee-Yung
- [46] Clinical molecular testing for ASXL1 c.1934dupG p.Gly646fs mutation in hematologic neoplasms in the NGS eraPLOS ONE, 2018, 13 (09):Montes-Moreno, SantiagoRoutbort, Mark J.Lohman, Elijah J.Barkoh, Bedia A.Kanagal-Shamanna, RashmiBueso-Ramos, Carlos E.Singh, Rajesh R.Medeiros, L. JeffreyLuthra, RajaPatel, Keyur P.
- [47] ASXL1 c.1934dup;p.Gly646Trpfs*12-a true somatic alteration requiring a new approachBLOOD CANCER JOURNAL, 2017, 7Yannakou, Costas K.Jones, KateMcBean, MichelleThompson, Ella R.Ryland, Georgina L.Doig, KenMarkham, JohnWesterman, DavidBlombery, Piers
- [48] Modeling ASXL1 mutation revealed impaired hematopoiesis caused by derepression of p16Ink4a through aberrant PRC1-mediated histone modificationLEUKEMIA, 2019, 33 (01) : 191 - 204Uni, MasahiroMasamoto, YosukeSato, TomohikoKamikubo, YasuhikoArai, ShunyaHara, EijiKurokawa, Mineo
- [49] Significance of SF3B1 Mutations in Myeloid NeoplasmsCLINICS IN LABORATORY MEDICINE, 2023, 43 (04) : 597 - 606Gajzer, David C.Yeung, Cecilia C. S.
- [50] Impact of the variant allele frequency of ASXL1, DNMT3A, JAK2, TET2, TP53, and NPM1 on the outcomes of patients with newly diagnosed acute myeloid leukemiaCANCER, 2020, 126 (04) : 765 - 774Sasaki, KojiKanagal-Shamanna, RashmiMontalban-Bravo, GuillermoAssi, RitaJabbour, EliasRavandi, FarhadKadia, TapanPierce, SherryTakahashi, KoichiGonzalez, Graciela NoguerasPatel, KeyurSoltysiak, Kelly A.Cortes, JorgeKantarjian, HagopGarcia-Manero, Guillermo