Review Potential drugs for the treatment of the novel coronavirus pneumonia (COVID-19) in China

被引：51
作者：
Pan, Xiaoqi [1 ,2 ]
Dong, Lan [3 ]
Yang, Lian [1 ,2 ]
Chen, Dayi [1 ,2 ]
Peng, Cheng [1 ,2 ]
机构：
[1] Chengdu Univ Tradit Chinese Med, Sch Publ Hlth, Chengdu 611137, Peoples R China
[2] Chengdu Univ Tradit Chinese Med, Sch Pharm, Chengdu 611137, Sichuan, Peoples R China
[3] Third Peoples Hosp Chengdu, Chengdu 610031, Peoples R China
来源：
VIRUS RESEARCH | 2020年 / 286卷
基金：
中国国家自然科学基金; 中国博士后科学基金;
关键词：
COVID-19; SARS-CoV-2; Chemical drugs; Traditional Chinese medicines; Biological products; RESPIRATORY SYNCYTIAL VIRUS; ANTIVIRAL ACTIVITY; IN-VITRO; MERS-COV; FAVIPIRAVIR T-705; COXSACKIE-VIRUS; EBOLA-VIRUS; SARS; RIBAVIRIN; INJECTION;
D O I：
10.1016/j.virusres.2020.198057
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
The fight against the novel coronavirus pneumonia (namely COVID-19) that seriously harms human health is a common task for all mankind. Currently, development of drugs against the novel coronavirus (namely SARSCoV-2) is quite urgent. Chinese medical workers and scientific researchers have found some drugs to play potential therapeutic effects on COVID-19 at the cellular level or in preliminary clinical trials. However, more fundamental studies and large sample clinical trials need to be done to ensure the efficacy and safety of these drugs. The adoption of these drugs without further testing must be careful. The relevant articles, news, and government reports published on the official and Preprint websites, PubMed and China National Knowledge Infrastructure (CNKI) databases from December 2019 to April 2020 were searched and manually filtered. The general pharmacological characteristics, indications, adverse reactions, general usage, and especially current status of the treatment of COVID-19 of those potentially effective drugs, including chemical drugs, traditional Chinese medicines (TCMs), and biological products in China were summarized in this review to guide reasonable medication and the development of specific drugs for the treatment of COVID-19.
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页数：12
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