A new approach for cellular immunotherapy of nasopharyngeal carcinoma

被引：11
作者：
Smith, Corey
Khanna, Rajiv [1 ]
机构：
[1] Queensland Inst Med Res, Australian Ctr Vaccine Dev, Brisbane, Qld 4006, Australia
来源：
ONCOIMMUNOLOGY | 2012年 / 1卷 / 08期
关键词：
T cells; HLA; immunotherapy; EBV; adenovirus; epitope; nasopharyngeal carcinoma; CD8(+) T-CELLS; LYMPHOCYTES;
D O I：
10.4161/onci.21286
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Nasopharyngeal carcinoma (NPC) is an Epstein-Barr virus (EBV)-associated malignancy that is highly prevalent in Southern China and South-East Asia. EBV-targeted immunotherapy remains a goal in the development of novel treatment strategies. A novel adenoviral polyepitope-based immunotherapy has been developed to rapidly generate high frequency EBV-specific T cells to treat patients with refractory or metastatic disease.
引用
收藏
页码：1440 / 1442
页数：3
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