A new approach for cellular immunotherapy of nasopharyngeal carcinoma

被引：11

作者：

Smith, Corey

Khanna, Rajiv ^{[1
]}

机构：

[1] Queensland Inst Med Res, Australian Ctr Vaccine Dev, Brisbane, Qld 4006, Australia

来源：

ONCOIMMUNOLOGY | 2012年 / 1卷 / 08期

关键词：

T cells; HLA; immunotherapy; EBV; adenovirus; epitope; nasopharyngeal carcinoma; CD8(+) T-CELLS; LYMPHOCYTES;

D O I：

10.4161/onci.21286

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Nasopharyngeal carcinoma (NPC) is an Epstein-Barr virus (EBV)-associated malignancy that is highly prevalent in Southern China and South-East Asia. EBV-targeted immunotherapy remains a goal in the development of novel treatment strategies. A novel adenoviral polyepitope-based immunotherapy has been developed to rapidly generate high frequency EBV-specific T cells to treat patients with refractory or metastatic disease.

引用

收藏

页码：1440 / 1442

页数：3

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