Monoalkylation of primary amines and N-sulfinylamides

被引：40

作者：

Garcia Ruano, Jose Luis ^{[1
]}

Parra, Alejandro ^{[1
]}

Aleman, Jose ^{[1
]}

Yuste, Francisco ^{[2
]}

Mastranzo, Virginia M. ^{[2
]}

机构：

[1] Univ Autonoma Madrid, Dept Quim Organ, E-28049 Madrid, Spain

[2] Univ Nacl Autonoma Mexico, Inst Quim, Mexico City 04510, DF, Mexico

来源：

CHEMICAL COMMUNICATIONS | 2009年 / 04期

关键词：

REDUCTIVE AMINATION; SECONDARY ALCOHOLS; ALKYLATION; SPERMIDINE; ALDEHYDES; NITRILES; REAGENT; KETONES; IMINES;

D O I：

10.1039/b816846f

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

An efficient monoalkylation of primary amines with primary or secondary alcohols catalyzed by Ra-Ni under mild conditions is described.

引用

页码：404 / 406

页数：3

共 35 条

[1] A review on the use of sodium triacetoxyborohydride in the reductive amination of ketones and aldehydes [J].

Abdel-Magid, Ahmed F. ;

Mehrman, Steven J. .

ORGANIC PROCESS RESEARCH & DEVELOPMENT, 2006, 10 (05) :971-1031

[2] CATALYTIC SYNTHESIS OF HIGHER ALIPHATIC-AMINES FROM THE CORRESPONDING ALCOHOLS [J].

BAIKER, A ;

KIJENSKI, J .

CATALYSIS REVIEWS-SCIENCE AND ENGINEERING, 1985, 27 (04) :653-697

[3] A comparison of structure-activity relationships between spermidine and spermine analogue antineoplastics [J].

Bergeron, RJ ;

Feng, Y ;

Weimar, WR ;

McManis, JS ;

Dimova, H ;

Porter, C ;

Raisler, B ;

Phanstiel, O .

JOURNAL OF MEDICINAL CHEMISTRY, 1997, 40 (10) :1475-1494

[4]

Blagbrough I.S., 1997, PHARM SCI-IRAN, V3, P223

[5] An efficient method for the selective iridium-catalyzed monoalkylation of (hetero)aromatic amines with primary alcohols [J].

Blank, Benoit ;

Madalska, Martyna ;

Kempe, Rhett .

ADVANCED SYNTHESIS & CATALYSIS, 2008, 350 (05) :749-758

[6]

BOTTA M, 1977, SYNTHESIS-STUTTGART, P722

[7] PREPARATION OF DIAMINO ETHERS AND POLYAMINES [J].

BRADSHAW, JS ;

KRAKOWIAK, KE ;

IZATT, RM .

TETRAHEDRON, 1992, 48 (22) :4475-4515

[8] Ready N-alkylation of enantiopure aminophenols:: synthesis of tertiary aminophenols [J].

Cimarelli, C ;

Palmieri, G ;

Volpini, E .

TETRAHEDRON, 2001, 57 (28) :6089-6096

[9]

DEANGELIS MB, 1979, SYNTHESIS-STUTTGART, P7

[10] N-tert-Butanesulfinyl imines:: Versatile intermediates for the asymmetric synthesis of amines [J].

Ellman, JA ;

Owens, TD ;

Tang, TP .

ACCOUNTS OF CHEMICAL RESEARCH, 2002, 35 (11) :984-995

← 1 2 3 4 →