Osteoarticular Infections in Children

被引:107
作者
Arnold, John C. [1 ]
Bradley, John S. [2 ]
机构
[1] Naval Med Ctr, Pediat & Infect Dis, San Diego, CA 92134 USA
[2] Univ Calif San Diego, Sch Med, Rady Childrens Hosp San Diego, Div Infect Dis,Dept Pediat, San Diego, CA 92103 USA
关键词
Pediatric; Osteoarticular infection; Acute bacterial osteomyelitis; Acute bacterial arthritis; Septic arthritis; Hematogenous; C-reactive protein (CRP); RESISTANT STAPHYLOCOCCUS-AUREUS; ACUTE HEMATOGENOUS OSTEOMYELITIS; C-REACTIVE PROTEIN; INDUCIBLE CLINDAMYCIN RESISTANCE; ERYTHROCYTE SEDIMENTATION-RATE; POLYMERASE-CHAIN-REACTION; JOINT INFECTIONS; SEPTIC ARTHRITIS; ANTIMICROBIAL TREATMENT; RANDOMIZED-TRIAL;
D O I
10.1016/j.idc.2015.05.012
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
For a child with a suspected bone or joint infection, knowledge of the workup and initial therapy is important to provide quality care. Fever and pain are hallmarks of a pediatric osteoarticular infection, although occasionally the signs and symptoms can be more subtle. The use of C-reactive protein to diagnose and validate effective management of treatment has become standard. Multiple reports confirm the success of much shorter intravenous (IV) courses than traditionally taught. The ideal IV and oral antibiotic duration, as well as defining the markers indicating need for surgical intervention, are questions yet to be answered.
引用
收藏
页码:557 / +
页数:20
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