Bilateral motor cortex output with intended unimanual contraction in congenital mirror movements

被引:40
|
作者
Cincotta, M
Borgheresi, A
Boffi, P
Vigliano, P
Ragazzoni, A
Zaccara, G
Ziemann, U
机构
[1] Santa Maria Nuova Hosp, Neurol Unit, Florence, Italy
[2] Univ Turin, Dept Neuropediat, I-10124 Turin, Italy
[3] JW Goethe Univ, Dept Neurol, Frankfurt, Germany
关键词
D O I
10.1212/WNL.58.8.1290
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
In congenital mirror movements (MM), it is unclear whether the "mirror" motor cortex (M1) produces output during intended unimanual movements. In two patients with MM, the cortical silent period (CSP) was abnormally short after focal transcranial magnetic stimulation (TMS) of either M1, but simultaneous bilateral TMS led to significant CSP lengthening. Thus, it is likely that the shortened CSP after unilateral TMS is caused by output from the nonstimulated M1, suggesting that both M1 produce output with intended unimanual movements in patients with MM.
引用
收藏
页码:1290 / 1293
页数:4
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