Analgesic effect of a polypeptide inhibitor of the TRPV1 receptor in noxious heat pain models

被引：13
作者：
Andreev, Ya. A. [1 ]
Kozlov, S. A. [1 ]
Kozlovskaya, E. P. [2 ]
Grishin, E. V. [1 ]
机构：
[1] Russian Acad Sci, Shemyakin Ovchinnikov Inst Bioorgan Chem, Moscow 117997, Russia
[2] Russian Acad Sci, Far E Div, Pacific Inst Bioorgan Chem, Vladivostok 690022, Russia
来源：
DOKLADY BIOCHEMISTRY AND BIOPHYSICS | 2009年 / 424卷 / 01期
关键词：
VANILLOID RECEPTOR; NOCICEPTION; ANTAGONIST; PEPTIDES; BLOCKERS;
D O I：
10.1134/S160767290901013X
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
[No abstract available]
引用
收藏
页码：46 / 48
页数：3
相关论文
共 11 条
[1]   The vanilloid receptor: A molecular gateway to the pain pathway [J].
Caterina, MJ ;
Julius, D .
ANNUAL REVIEW OF NEUROSCIENCE, 2001, 24 :487-517
[2]   Impaired nociception and pain sensation in mice lacking the capsaicin receptor [J].
Caterina, MJ ;
Leffler, A ;
Malmberg, AB ;
Martin, WJ ;
Trafton, J ;
Petersen-Zeitz, KR ;
Koltzenburg, M ;
Basbaum, AI ;
Julius, D .
SCIENCE, 2000, 288 (5464) :306-313
[3]   Attenuation of thermal nociception and hyperalgesia by VR1 blockers [J].
García-Martínez, C ;
Humet, M ;
Planells-Cases, R ;
Gomis, A ;
Caprini, M ;
Viana, F ;
De la Peña, E ;
Sanchez-Baeza, F ;
Carbonell, T ;
De Felipe, C ;
Pérez-Payá, E ;
Belmonte, C ;
Messeguer, A ;
Ferrer-Montiel, A .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2002, 99 (04) :2374-2379
[4]   The TRPV1 receptor and nociception [J].
Immke, David C. ;
Gavva, Narender R. .
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY, 2006, 17 (05) :582-591
[5]   A polyclonal antibody to the prepore loop of transient receptor potential vanilloid type 1 blocks channel activation [J].
Klionsky, Lana ;
Tamir, Rami ;
Holzinger, Bob ;
Bi, Xiaojuan ;
Talvenheimo, Jane ;
Kim, Helen ;
Martin, Frank ;
Louis, Jean-Claude ;
Treanor, James J. S. ;
Gavva, Narender R. .
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 2006, 319 (01) :192-198
[6]   Conus peptides:: Biodiversity-based discovery and exogenomics [J].
Olivera, Baldomero M. .
JOURNAL OF BIOLOGICAL CHEMISTRY, 2006, 281 (42) :31173-31177
[7]   Arginine-rich peptides are blockers of VR-1 channels with analgesic activity [J].
Planells-Cases, R ;
Aracil, A ;
Merino, JM ;
Gallar, J ;
Pérez-Payá, E ;
Belmonte, C ;
González-Ros, JM ;
Ferrer-Montiel, AV .
FEBS LETTERS, 2000, 481 (02) :131-136
[8]  
RAMI HK, 2004, DRUG DISCOV TODAY, V1, P97
[9]  
SCHIM JD, 2004, PAIN PRACT S1, V4, P4
[10]   The vanilloid receptor TRPV1: 10 years from channel cloning to antagonist proof-of-concept [J].
Szallasi A. ;
Cortright D.N. ;
Blum C.A. ;
Eid S.R. .
Nature Reviews Drug Discovery, 2007, 6 (5) :357-372
12