Synthesis and rearrangement of 3-methyl-1,4-pentadiyne-3-ol

被引：7

作者：

Buser, D ^{[1
]}

Pauling, H ^{[1
]}

Thum, A ^{[1
]}

Bonrath, W ^{[1
]}

机构：

[1] Roche Vitamins Ltd, Vitamins Res & Technol Dev, CH-4070 Basel, Switzerland

来源：

MOLECULES | 2002年 / 7卷 / 03期

关键词：

alpha; beta-unsaturated carbonyl compound; alpha-alkynols; Meyer-Schuster rearrangement; perrhenate-catalysts; Mo(VI)-catalysts;

D O I：

10.3390/70300341

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

An efficient synthesis and rearrangement of 3-methyl-1,4-pentadiyne-3-ol (1) using perrhenate- and Mo(VI)-catalysts is reported. The by-products 3,6-dimethyl-1,4,7octatriyne-3,6-diol (2) and 3-ethynyl-5-methyl-1,6-heptadiyne-3,5-diol (3) were isolated and spectroscopically characterized. A possible reaction mechanism for the formation of the by products is discussed.

引用

页码：341 / 352

页数：12

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