AlCl3 mediated three component cyclocondensation for the synthesis of 5-unsubstituted 3,4-dihydropyrimidin-2(1H)-ones

被引：0
|
作者：
Saini, A [1 ]
Kumar, S [1 ]
Sandhu, JS [1 ]
机构：
[1] Punjabi Univ, Dept Chem, Patiala 147002, Punjab, India
来源：
INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY | 2006年 / 45卷 / 03期
关键词：
aluminium trichloride; potassium iodide; enolisalable ketone; addehyde; urea; 5-unsubstituted-3,4-dihydropyrimidin-2(1H)-ones;
D O I：
暂无
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
5-Unsubstituded-3,4-dihydropyrimidin-2(1H)-ones have been synthesized in excellent yields in aluminium trichloride mediated three component cyclocondensation of aldehyde, urea and enolisable ketones.
引用
收藏
页码：684 / 688
页数：5
相关论文
共 50 条
  • [1] Expedient synthesis of 5-unsubstituted 3,4-dihydropyrimidin-2(1H)-ones.
    Steele, TG
    Coburn, CA
    Patane, MA
    Bock, MG
    TETRAHEDRON LETTERS, 1998, 39 (51) : 9315 - 9318
  • [2] Novel Biginelli-like three-component cyclocondensation reaction:: efficient synthesis of 5-unsubstituted 3,4-dihydropyrimidin-2(1H)-ones
    Wang, ZT
    Xu, LW
    Xia, CG
    Wang, HQ
    TETRAHEDRON LETTERS, 2004, 45 (42) : 7951 - 7953
  • [3] A new substrate for the Biginelli cyclocondensation:: Direct preparation of 5-unsubstituted 3,4-dihydropyrimidin-2(1H)-ones from a β-keto carboxylic acid
    Bussolari, JC
    McDonnell, PA
    JOURNAL OF ORGANIC CHEMISTRY, 2000, 65 (20): : 6777 - 6779
  • [4] Novel Biginelli-like three-component cyclocondensation reaction:: efficient synthesis of 5-unsubstituted 3,4-dihydropyrimidin-2(1H)-ones (vol 45, pg 7951, 2004)
    Wang, ZT
    Xu, LW
    Xia, CG
    Wang, HQ
    TETRAHEDRON LETTERS, 2006, 47 (08) : 1361 - 1361
  • [5] Synthesis of 3,4-dihydropyrimidin-2(1H)-ones and 3,4,5,6,7,8-hexahydroquinazolin-2(1H)-ones via three component cyclocondensation
    Phucho, I. T.
    Nongpiur, A.
    Nongrum, R.
    Nongkhlaw, R. L.
    INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY, 2010, 49 (03): : 346 - 350
  • [6] Zeolite-catalyzed cyclocondensation reaction for the selective synthesis of 3,4-dihydropyrimidin-2(1H)-ones
    Rani, VR
    Srinivas, N
    Kishan, MR
    Kulkarni, SJ
    Raghavan, KV
    GREEN CHEMISTRY, 2001, 3 (06) : 305 - 306
  • [7] Iodotrimethylsilane-accelerated one-pot synthesis of 5-unsubstituted 3,4-dihydropyrimidin-2(1H)-ones:: A novel procedure for the Biginelli-like cyclocondensation reaction at room temperature
    Sabitha, G
    Reddy, KB
    Srinivas, R
    Yadav, JS
    HELVETICA CHIMICA ACTA, 2005, 88 (11) : 2996 - 2999
  • [8] Oxidation of 3,4-dihydropyrimidin-2(1H)-ones with nitrosonium(NO~+)
    Rui Rui Liang
    ChineseChemicalLetters, 2009, 20 (10) : 1183 - 1186
  • [9] A rapid and convenient synthesis of 5-unsubstituted 3,4-dihydropyrimidin-2-ones and thiones
    Fang, Zhanxiong
    Lam, Yulin
    TETRAHEDRON, 2011, 67 (06) : 1294 - 1297
  • [10] Heteropoly acid catalyzed synthesis of 3,4-dihydropyrimidin-2(1H)-ones
    Maradur, Sanjeev P.
    Gokavi, Gavisiddappa S.
    CATALYSIS COMMUNICATIONS, 2007, 8 (03) : 279 - 284
12345