Three-component one-pot reaction for the synthesis of β-amide ketones

被引：5
作者：
Luo, Yan-Ping [1 ]
Chen, Qiong [2 ]
机构：
[1] Hainan Univ, Key Lab Protect & Dev Utilisat Trop Crop Germplas, Minist Educ, Haikou 570228, Peoples R China
[2] Cent China Normal Univ, Key Lab Pesticide & Chem Biol, Minist Educ, Coll Chem, Wuhan 430079, Peoples R China
来源：
CHEMICAL PAPERS | 2013年 / 67卷 / 05期
基金：
中国国家自然科学基金;
关键词：
beta-amide ketones; one-pot reaction; synthesis; DAKIN-WEST REACTION; ACETAMIDO KETONES; EFFICIENT; CATALYST; PROPARGYLAMINES; ALDEHYDES; ALKYNES; ACIDS;
D O I：
10.2478/s11696-013-0313-0
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
beta-amide ketones were synthesised by a three-component one-pot reaction of phenylacetylene, aldehydes, and amides in anhydrous acetonitrile containing trifluoroacetic acid and acetic acid in the presence of AlCl3 catalyst. The title compound structures were identified by H-1 NMR, C-13 NMR, MS, and elemental analysis.
引用
收藏
页码：532 / 537
页数：6
相关论文
共 50 条
  • [21] One-pot, three-component synthesis of pyranocoumarins containing an aroyl group
    Khodabakhshi, Saeed
    Jafari, Fariba
    Marahel, Farzaneh
    Baghernejad, Mojtaba
    HETEROCYCLIC COMMUNICATIONS, 2014, 20 (05) : 285 - 288
  • [22] A novel one-pot three-component synthesis of benzofuran derivatives via Strecker reaction: Study of antioxidant activity
    Ezzatzadeh, Elham
    Hossaini, Zinatossadat
    NATURAL PRODUCT RESEARCH, 2020, 34 (07) : 923 - 929
  • [23] One-Pot, Three-Component Assembly of Indoloquinolines: Total Synthesis of Isocryptolepine
    Aksenov, Alexander V.
    Aksenov, Dmitrii A.
    Orazova, Naila A.
    Aksenov, Nicolai A.
    Griaznov, Georgii D.
    De Carvalho, Annelise
    Kiss, Robert
    Mathieu, Veronique
    Kornienko, Alexander
    Rubin, Michael
    JOURNAL OF ORGANIC CHEMISTRY, 2017, 82 (06) : 3011 - 3018
  • [24] One-Pot Three-Component Access to Furan and Thiophene Derivatives
    Bao, Ruipeng
    Wang, Yao
    Lin, Xinbo
    Tan, Jinglin
    Chen, Zhihua
    Wang, Teng
    Yu, Xinhong
    SYNLETT, 2025, 36 (07) : 841 - 844
  • [25] An Efficient One-pot Three-component Process for Synthesis of Perfluoroalkylated Quinolizines
    Shen, Dandan
    Xu, Yanjie
    He, Dong
    Han, Jing
    Chen, Jie
    Deng, Hongmei
    Shao, Min
    Zhang, Hui
    Cao, Weiguo
    CHINESE JOURNAL OF CHEMISTRY, 2016, 34 (05) : 524 - 532
  • [26] One-Pot Three-Component Synthesis of Novel Carbamate Compounds Mediated by Zinc Powder
    Meng, Tuanjie
    Liu, Lantao
    Ren, Lifeng
    Liu, Xinming
    Wang, Xiaojuan
    Zhao, Wenxian
    CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2014, 34 (08) : 1588 - 1594
  • [27] Convenient One-Pot Three-Component Synthesis of Trifluoromethylated Tetrahydrobenzo[g]chromene Derivatives
    Duan, Yijun
    Wang, Xu
    Xu, Xiaoling
    Kang, Zhangping
    Zhang, Min
    Song, Liping
    Deng, Hongmei
    SYNTHESIS-STUTTGART, 2013, 45 (15): : 2193 - 2200
  • [28] Sulfamic acid promoted one-pot three-component synthesis and cytotoxic evaluation of spirooxindoles
    Kamal, Ahmed
    Babu, Korrapati Suresh
    Vardhan, M. V. P. S. Vishnu
    Hussaini, S. M. Ali
    Mahesh, Rasala
    Shaik, Siddiq Pasha
    Alarifi, Abdullah
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2015, 25 (10) : 2199 - 2202
  • [29] One-pot, three-component Mannich-type reaction catalyzed by functionalized ionic liquid
    Fang, Dong
    Gong, Kai
    Zhang, Dai-zhen
    Liu, Zu-liang
    MONATSHEFTE FUR CHEMIE, 2009, 140 (11): : 1325 - 1329
  • [30] One-pot, three-component Mannich-type reaction catalyzed by functionalized ionic liquid
    Dong Fang
    Kai Gong
    Dai-zhen Zhang
    Zu-liang Liu
    Monatshefte für Chemie - Chemical Monthly, 2009, 140 : 1325 - 1329
12345