Cytokine gene polymorphisms in Iraqi Arabs

被引：8

作者：

Ad'hiah, Ali H. ^{[1
]}

Ahmed, Zahra'a A. ^{[2
]}

Al-Naseri, Milad A. ^{[3
]}

Salman, Ehab D. ^{[4
]}

Al-saffar, Osama B. ^{[5
]}

Ahmed, Hiba S. ^{[6
]}

Hussain, Talib A. ^{[2
]}

Idan, Ekhlass M. ^{[2
]}

Hassan, Ibtesam B. ^{[7
]}

Shihab, Batool A. ^{[2
]}

Mohammed, Lateef O. ^{[8
]}

Al-Nasiri, Fatima S. ^{[9
]}

机构：

[1] Univ Baghdad, Coll Sci, Trop Biol Res Unit, Baghdad, Iraq

[2] Univ Baghdad, Coll Sci Women, Dept Biol, Baghdad, Iraq

[3] Minist Hlth, Sera & Vaccine Inst, Baghdad, Iraq

[4] Univ Baghdad, Coll Sci, Dept Biotechnol, Baghdad, Iraq

[5] Madenat Alelem Univ Coll, Dept Biol, Baghdad, Iraq

[6] Al Karkh Univ Sci, Coll Sci, Dept Microbiol, Baghdad, Iraq

[7] Univ Diyala, Coll Educ Pure Sci, Dept Life Sci, Diyala, Iraq

[8] Univ Sulaimania, Coll Med, Dept Med Microbiol, Sulaimania, Iraq

[9] Univ Tikrit, Coll Sci, Dept Biol, Tikrit, Iraq

来源：

HUMAN IMMUNOLOGY | 2018年 / 79卷 / 02期

关键词：

Iraqi Arabs; Cytokine; SNPs; Haplotype;

D O I：

10.1016/j.humimm.2017.12.009

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

In this report, 224 unrelated healthy Iraqi Arabs (102 males and 122 females) were genotyped for 22 SNPs (single nucleotide polymorphisms) belong to 13 cytokine genes (ILIA, 1L1B, 1L1RA, IL1R, 1L2, 1L4, 1L4R, IL6, 1L10, 1L12, IFNG, TNFA and TGFB1). The method of detection was PCR-SSP (polymerase chain reaction -sequence specific primer). The data were presented in terms of allele and genotype frequencies. Two -locus haplotype frequencies were also estimated for some SNPs. Genotype frequencies of detected cytokine gene polymorphisms are available in the Database of Allele Frequencies Net under the AFND number 3422 and the population name "Iraq Arab Cytokine".

引用

页码：91 / 92

页数：2

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