Pulmonary complications after Esophagectomy

被引:252
作者
Avendano, CE
Flume, PA
Silvestri, GA
King, LB
Reed, CE
机构
[1] Med Univ S Carolina, Dept Med, Charleston, SC 29425 USA
[2] Med Univ S Carolina, Dept Biometry & Epidemiol, Charleston, SC 29425 USA
[3] Med Univ S Carolina, Dept Surg, Charleston, SC 29425 USA
关键词
D O I
10.1016/S0003-4975(01)03584-6
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Background. Pulmonary complications are common in patients who have undergone esophagectomy. There are no good predictive variables for these complications. In addition, the role that preoperative treatment with chemotherapy and radiation may play in postoperative complications remains unclear. Methods. We performed a retrospective review of all patients who underwent esophagectomy by a single surgeon at our institution over a 6-year period. Data were analyzed for a correlation between patient risk factors and pulmonary complications, including mortality, prolonged mechanical ventilation, and hospital length of stay. Results. Complete data were available on 61 patients. Nearly all patients had some pulmonary abnormality (eg, pleural effusion), although most of these were clinically insignificant. Pneumonia was the most common clinically important complication, and 19.7% of patients required prolonged ventilatory support. Significant risk factors identified included impaired pulmonary function, especially for patients with forced expiratory volume in 1 second (FEV1) less than 65% of predicted, preoperative chemoradiotherapy, and age. Conclusions. Impaired lung function is a significant risk factor for pulmonary complications after esophagectomy. Patients with FEV1 less than 65% of predicted appear to be at greatest risk. There also seems to be an associated risk of preoperative chemoradiotherapy for pulmonary complications after esophagectomy. (C) 2002 by The Society of Thoracic Surgeons.
引用
收藏
页码:922 / 926
页数:5
相关论文
共 33 条
  • [1] ESOPHAGEAL RESECTION AND BYPASS - A 6 YEAR EXPERIENCE WITH A LOW POSTOPERATIVE MORTALITY
    COLLARD, JM
    OTTE, JB
    REYNAERT, M
    MICHEL, L
    CARLIER, MA
    KESTENS, PJ
    [J]. WORLD JOURNAL OF SURGERY, 1991, 15 (05) : 635 - 641
  • [2] Eguchi R, 1999, Jpn J Thorac Cardiovasc Surg, V47, P552
  • [3] PREDICTION OF POSTOPERATIVE PULMONARY COMPLICATIONS IN ESOPHAGOGASTRIC CANCER-SURGERY
    FAN, ST
    LAU, WY
    YIP, WC
    POON, GP
    YEUNG, C
    LAM, WK
    WONG, KK
    [J]. BRITISH JOURNAL OF SURGERY, 1987, 74 (05) : 408 - 410
  • [4] Mortality after esophagectomy: Risk factor analysis
    Ferguson, MK
    Martin, TR
    Reeder, LB
    Olak, J
    [J]. WORLD JOURNAL OF SURGERY, 1997, 21 (06) : 599 - 604
  • [5] OPERABLE ESOPHAGEAL-CARCINOMA - CURRENT RESULTS FROM HONG-KONG
    FOK, M
    LAW, SYK
    WONG, J
    [J]. WORLD JOURNAL OF SURGERY, 1994, 18 (03) : 355 - 360
  • [6] TREATMENT OF CARCINOMA OF THE ESOPHAGUS - RETROSPECTIVE STUDY OF 2,400 PATIENTS
    GIULI, R
    GIGNOUX, M
    [J]. ANNALS OF SURGERY, 1980, 192 (01) : 44 - 52
  • [7] PRELIMINARY-RESULTS WITH NEOADJUVANT THERAPY AND RESECTION FOR ESOPHAGEAL-CARCINOMA
    HOFF, SJ
    STEWART, JR
    SAWYERS, JL
    MURRAY, MJ
    MERRILL, WH
    ADKINS, RB
    JOHNSON, DH
    ORRINGER, MB
    GINSBERG, RJ
    COOLEY, DA
    [J]. ANNALS OF THORACIC SURGERY, 1993, 56 (02) : 282 - 287
  • [8] ILSON DH, 1994, SEMIN ONCOL, V21, P493
  • [9] Kuwano H, 1998, EUR J SURG, V164, P581
  • [10] RISK ANALYSIS IN RESECTION OF SQUAMOUS-CELL CARCINOMA OF THE ESOPHAGUS
    LAW, SYK
    FOK, M
    WONG, J
    [J]. WORLD JOURNAL OF SURGERY, 1994, 18 (03) : 339 - 346