LTD and LTP induced by transcranial magnetic stimulation in auditory cortex

被引：164

作者：

Wang, H ^{[1
]}

Wang, X ^{[1
]}

Scheich, H ^{[1
]}

机构：

[1] FED INST NEUROBIOL,D-39008 MAGDEBURG,GERMANY

来源：

NEUROREPORT | 1996年 / 7卷 / 02期

关键词：

magnetic stimulation; population spikes; plasticity; auditorycortex; mongolian gerbil;

D O I：

10.1097/00001756-199601310-00035

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

USING a system capable of relatively localized and rapid-rate transcranial magnetic stimulation (rTMS), evoked trains of complex spikes were studied in rodent auditory cortex. Low rate rTMS from 1 to 10 Hz produced a frequency-dependent increase in spike rate. Iterations of rTMS resulted in long-term potentiation (LTP)-like, and more durable long-term depression (LTD)-like changes in evoked spike rate. These observations generate new perspectives for studying mechanisms of learning and memory non-invasively as well as introducing some caveats for use of rTMS in humans.

引用

页码：521 / 525

页数：5

共 22 条

[1] LONG-TERM DEPRESSION OF EXCITATORY SYNAPTIC TRANSMISSION AND ITS RELATIONSHIP TO LONG-TERM POTENTIATION [J].