High sensitive determination of theophylline based on gold nanoparticles/L-cysteine/Graphene/Nafion modified electrode

被引：33
作者：
Zi, Lijuan [1 ]
Li, Jianjun [1 ]
Mao, Yexuan [1 ]
Yang, Ran [1 ]
Qu, Lingbo [1 ,2 ]
机构：
[1] Zhengzhou Univ, Coll Chem & Mol Engn, Zhengzhou 450001, Peoples R China
[2] Henan Univ Technol, Sch Chem & Chem Engn, Zhengzhou 450001, Peoples R China
来源：
ELECTROCHIMICA ACTA | 2012年 / 78卷
关键词：
Gold nanoparticles (GNP); Graphenen (Gr); L-Cysteine (L-cys); Theophylline (TP); Modified electrode; MULTIWALLED CARBON NANOTUBES; VOLTAMMETRIC DETERMINATION; ELECTROCHEMICAL OXIDATION; CAFFEINE; XANTHINE; SERUM;
D O I：
10.1016/j.electacta.2012.06.018
中图分类号：
O646 [电化学、电解、磁化学];
学科分类号：
081704 ;
摘要：
In the work described on this paper, a gold nanoparticles (GNP)/L-cysteine (L-cys)/Graphene (Gr)/Nafion composite film modified glass carbon electrode (GCE) was fabricated and characterized. The modified electrode showed excellent electrocatalytic activity towards the oxidation of theophylline (TP) in 0.1 mol L-1 H2SO4 medium. Differential pulse voltammetry (DPV) was used for the determination of TP. Under the optimum conditions, the peak current of TP was proportional to its concentration at the range of 4.0 x 10(-9) to 6.0 x 10(-5) mol L-1 with a detection limit 4.0 x 10(-10) mol L-1. The newly developed method was successfully applied for the determination of TP in tea samples and pharmaceutical tablets with good percentage of recoveries. (C) 2012 Elsevier Ltd. All rights reserved,
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页码：434 / 439
页数：6
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