Biomimetic Surface Engineering of Lanthanide-Doped Upconversion Nanoparticles as Versatile Bioprobes

被引：238

作者：

Li, Le-Le ^{[1
]}

Zhang, Ruobing ^{[2
]}

Yin, Leilei ^{[1
]}

Zheng, Kezhi ^{[3
]}

Qin, Weiping ^{[3
]}

Selvin, Paul R. ^{[2
]}

Lu, Yi ^{[1
]}

机构：

[1] Univ Illinois, Dept Chem, Beckman Inst Adv Sci & Technol, Urbana, IL 61801 USA

[2] Univ Illinois, Dept Phys, Ctr Phys Living Cells, Urbana, IL 61801 USA

[3] Jilin Univ, State Key Lab Integrated Optoelect, Coll Elect Sci & Engn, Changchun 130012, Peoples R China

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2012年 / 51卷 / 25期

基金：

美国国家科学基金会;

关键词：

imaging agents; lanthanides; luminescence; nanoparticles; phospholipids; IRON-OXIDE NANOPARTICLES; QUANTUM DOTS; DRUG-DELIVERY; NANOCRYSTALS; FLUORESCENCE; LIPOSOMES; NANOSTRUCTURES; LUMINESCENCE; EMISSION; CELLS;

D O I：

10.1002/anie.201109156

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Coat of lipids: Water-dispersible and functionalizable upconverting nanoparticles (UCNPs) for selective imaging of live cancer cells were synthesized. The synthetic approach involves coating the surface of the UCNPs with a monolayer of phospholipids that contain different functional groups (see picture), thus allowing for conjugation of many molecules for applications in fields such as bioinspired nanoassembly, biosensing, and biomedicine. Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

引用

页码：6121 / 6125

页数：5

共 64 条

[1] Hard Proof of the NaYF4/NaGdF4 Nanocrystal Core/Shell Structure [J].

Abel, Keith A. ;

Boyer, John-Christopher ;

van Veggel, Frank C. J. M. .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2009, 131 (41) :14644-+

[2] Liposomes: From a Clinically Established Drug Delivery System to a Nanoparticle Platform for Theranostic Nanomedicine [J].

Al-Jamal, Wafa' T. ;

Kostarelos, Kostas .

ACCOUNTS OF CHEMICAL RESEARCH, 2011, 44 (10) :1094-1104

[3]

[Anonymous], ANGEW CHEM, DOI DOI 10.1002/ANGE.201003959

[4]

[Anonymous], 2011, ANGEW CHEM

[5]

Ashley CE, 2011, NAT MATER, V10, P389, DOI [10.1038/NMAT2992, 10.1038/nmat2992]

[6] Upconversion and anti-stokes processes with f and d ions in solids [J].

Auzel, F .

CHEMICAL REVIEWS, 2004, 104 (01) :139-173

[7] Synthesis of Ligand-Free Colloidally Stable Water Dispersible Brightly Luminescent Lanthanide-Doped Upconverting Nanoparticles [J].

Bogdan, Nicoleta ;

Vetrone, Fiorenzo ;

Ozin, Geoffrey A. ;

Capobianco, John A. .

NANO LETTERS, 2011, 11 (02) :835-840

[8] Semiconductor nanocrystals as fluorescent biological labels [J].

Bruchez, M ;

Moronne, M ;

Gin, P ;

Weiss, S ;

Alivisatos, AP .

SCIENCE, 1998, 281 (5385) :2013-2016

[9] Synthesis, encapsulation, purification and coupling of single quantum dots in phospholipid micelles for their use in cellular and in vivo imaging [J].

Carion, Olivier ;

Mahler, Benoit ;

Pons, Thomas ;

Dubertret, Benoit .

NATURE PROTOCOLS, 2007, 2 (10) :2383-2390

[10]

Carling C.J., 2010, Angewandte Chemie, V122, P3870, DOI DOI 10.1002/ANGE.201000611

← 1 2 3 4 5 6 7 →