Addison's disease secondary to connective tissue diseases: a report of six cases

被引：11

作者：

Zhang, Zhuo-li ^{[1
]}

Wang, Yu ^{[1
]}

Zhou, Wei ^{[1
]}

Hao, Yan-jie ^{[1
]}

机构：

[1] Beijing Univ, Hosp 1, Dept Rheumatol & Clin Immunol, Beijing 100034, Peoples R China

来源：

RHEUMATOLOGY INTERNATIONAL | 2009年 / 29卷 / 06期

关键词：

Addison's disease; Autoimmunity; Connective tissue diseases; PRIMARY ANTIPHOSPHOLIPID SYNDROME; ADRENAL INSUFFICIENCY; AUTOIMMUNITY; ASSOCIATION;

D O I：

10.1007/s00296-008-0749-7

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Addison's disease is an autoimmune process. However, Addison's disease associated with connective tissue diseases (CTD) is only occasionally reported. Here, we report six cases of Addison's disease secondary to a variety of CTD, which include systemic lupus erythematosus, Takayasu arteritis, systemic sclerosis, ankylosing spondylitis (AS) and antiphospholipid antibody syndrome. The association of Addison's disease with Takayasu arteritis and AS is reported for the first time. We also found high prevalence of hypothyroidism as concomitant autoimmune disorder. Our case series highlight the autoimmune features of Addison's disease. Therefore, we suggest considering adrenal dysfunction in patients with CTD.

引用

页码：647 / 650

页数：4

共 15 条

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