Management of locoregional recurrence in cutaneous squamous cell carcinoma of the head and neck

被引:13
作者
Strassen, Ulrich [1 ]
Hofauer, Benedikt [1 ]
Jacobi, Christian [2 ]
Knopf, Andreas [1 ]
机构
[1] Klinikum Rechts Der Isar, Otorhinolaryngol Head & Neck Surg, Ismaningerstr 22, D-81675 Munich, Germany
[2] Klinikum Grosshadern, Otorhinolaryngol Head & Neck Surg, Munich, Germany
关键词
Cutaneous squamous cell carcinoma; Head and neck; Outcome; Therapy; Recurrence; LYMPH-NODE METASTASIS; NONMELANOMA SKIN-CANCER; RISK-FACTORS; EPIDEMIOLOGY; MELANOMA;
D O I
10.1007/s00405-016-4243-7
中图分类号
R76 [耳鼻咽喉科学];
学科分类号
100213 ;
摘要
Cutaneous squamous cell carcinomas often affect elderly patients. Follow-up monitoring is difficult in these patients due to their multi-morbidity and reduced compliance. Tumour recurrence is consequently diagnosed in advanced tumour stages. Surgical therapy with curative intention often requires extended resections. The study at hand should determine whether surgical concepts are warranted in this collective. Sixty-seven patients who underwent surgical procedure due to recurrent disease of cutaneous head and neck squamous cell carcinoma were included. The cohort was divided in patients with/without adjuvant therapeutic regimens. Data were assessed retrospectively. Complete tumour resection was achieved in 85 % of our patients. Patients with adjuvant treatment demonstrated a favorable 5-year-recurrence-free interval (78 vs 30 %) and overall survival (79 vs 46 %). Complete surgical resection of advanced recurrent head and neck cutaneous squamous cell carcinomas is possible and yields favorable results in terms of survival, especially if combined with adjuvant treatment.
引用
收藏
页码:501 / 506
页数:6
相关论文
共 50 条
  • [41] Lymph node metastases from cutaneous squamous cell carcinoma of the head and neck
    Moore, BA
    Weber, RS
    Prieto, V
    El-Naggar, A
    Holsinger, FC
    Zhou, X
    Lee, JJ
    Lippman, S
    Clayman, GL
    LARYNGOSCOPE, 2005, 115 (09) : 1561 - 1567
  • [42] Head and neck squamous cell carcinoma in young patients
    van Monsjou, Hester S.
    Wreesmann, Volkert B.
    van den Brekel, Michiel W. M.
    Balm, Alfons J. M.
    ORAL ONCOLOGY, 2013, 49 (12) : 1097 - 1102
  • [43] Immunotherapy in the management of squamous cell carcinoma of the head and neck
    Subramaniam, S. S.
    Paterson, C.
    McCaul, J. A.
    BRITISH JOURNAL OF ORAL & MAXILLOFACIAL SURGERY, 2019, 57 (10) : 957 - 966
  • [44] Management of Cutaneous Squamous Cell Carcinoma of the Scalp: The Role of Imaging and Therapeutic Approaches
    Verdaguer-Faja, Julia
    Toll, Agusti
    Boada, Aram
    Guerra-Amor, Alvaro
    Ferrandiz-Pulido, Carla
    Jaka, Ane
    CANCERS, 2024, 16 (03)
  • [45] Immunotherapy for the Treatment of Cutaneous Squamous Cell Carcinoma
    Boutros, Andrea
    Cecchi, Federica
    Tanda, Enrica Teresa
    Croce, Elena
    Gili, Riccardo
    Arecco, Luca
    Spagnolo, Francesco
    Queirolo, Paola
    FRONTIERS IN ONCOLOGY, 2021, 11
  • [46] Multivariate analysis of potential risk factors for lymph node metastasis in patients with cutaneous squamous cell carcinoma of the head and neck
    Haisma, Marjolijn S.
    Plaat, Boudewijn E. C.
    Bijl, Hendrik P.
    Roodenburg, Jan L. N.
    Diercks, Gilles F. H.
    Romeijn, Tonnis R.
    Terra, Jorrit B.
    JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 2016, 75 (04) : 722 - 730
  • [47] Cutaneous Squamous Cell Carcinoma
    Leiter, U.
    Gutzmer, R.
    Alter, M.
    Ulrich, C.
    Lonsdorf, A. S.
    Sachse, M. M.
    Hillen, U.
    HAUTARZT, 2016, 67 (11): : 857 - 866
  • [48] Expression of haptoglobin predicts recurrence in head and neck squamous cell carcinoma
    Lee, Ching-Chih
    Ho, Hsu-Chueh
    Lee, Moon-Sing
    Hung, Shih-Kai
    Yu, Chih-Chia
    Su, Yu-Chieh
    CLINICA CHIMICA ACTA, 2010, 411 (15-16) : 1116 - 1121
  • [49] Immunosuppression and Outcomes in Patients with Cutaneous Squamous Cell Carcinoma of the Head and Neck
    Iancu, Doriana
    Fulga, Ana
    Vesa, Doina
    Fulga, Iuliu
    Tutunaru, Dana
    Zenovia, Andrei
    Piraianu, Alin Ionut
    Stamate, Elena
    Sterian, Corina
    Dimofte, Florentin
    Badea, Mihail Alexandru
    Tatu, Alin Laurentiu
    CLINICS AND PRACTICE, 2025, 15 (01)
  • [50] Lymph node metastasis in cutaneous squamous cell carcinoma of the head and neck
    Fang, Qigen
    Yuan, Junhui
    Zhang, Xu
    Dai, Liyuan
    Luo, Ruihua
    BMC CANCER, 2024, 24 (01)