Cutaneous squamous cell carcinoma;
Head and neck;
Outcome;
Therapy;
Recurrence;
LYMPH-NODE METASTASIS;
NONMELANOMA SKIN-CANCER;
RISK-FACTORS;
EPIDEMIOLOGY;
MELANOMA;
D O I:
10.1007/s00405-016-4243-7
中图分类号:
R76 [耳鼻咽喉科学];
学科分类号:
100213 ;
摘要:
Cutaneous squamous cell carcinomas often affect elderly patients. Follow-up monitoring is difficult in these patients due to their multi-morbidity and reduced compliance. Tumour recurrence is consequently diagnosed in advanced tumour stages. Surgical therapy with curative intention often requires extended resections. The study at hand should determine whether surgical concepts are warranted in this collective. Sixty-seven patients who underwent surgical procedure due to recurrent disease of cutaneous head and neck squamous cell carcinoma were included. The cohort was divided in patients with/without adjuvant therapeutic regimens. Data were assessed retrospectively. Complete tumour resection was achieved in 85 % of our patients. Patients with adjuvant treatment demonstrated a favorable 5-year-recurrence-free interval (78 vs 30 %) and overall survival (79 vs 46 %). Complete surgical resection of advanced recurrent head and neck cutaneous squamous cell carcinomas is possible and yields favorable results in terms of survival, especially if combined with adjuvant treatment.
机构:
Leiden Med Ctr, Dept Otorhinolaryngol, NL-2300 RC Leiden, NetherlandsLeiden Med Ctr, Dept Otorhinolaryngol, NL-2300 RC Leiden, Netherlands
van Monsjou, Hester S.
Wreesmann, Volkert B.
论文数: 0引用数: 0
h-index: 0
机构:
Mem Sloan Kettering Canc Ctr, Head & Neck Serv, Dept Surg, New York, NY 10065 USALeiden Med Ctr, Dept Otorhinolaryngol, NL-2300 RC Leiden, Netherlands
机构:
Tzu Chi Univ, Sch Med, Hualien, Taiwan
Buddhist Dalin Tzu Chi Gen Hosp, Dept Otolaryngol, Chiayi, TaiwanTzu Chi Univ, Sch Med, Hualien, Taiwan
Lee, Ching-Chih
Ho, Hsu-Chueh
论文数: 0引用数: 0
h-index: 0
机构:
Tzu Chi Univ, Sch Med, Hualien, Taiwan
Buddhist Dalin Tzu Chi Gen Hosp, Dept Otolaryngol, Chiayi, TaiwanTzu Chi Univ, Sch Med, Hualien, Taiwan
Ho, Hsu-Chueh
Lee, Moon-Sing
论文数: 0引用数: 0
h-index: 0
机构:
Tzu Chi Univ, Sch Med, Hualien, Taiwan
Buddhist Dalin Tzu Chi Gen Hosp, Dept Radiat Oncol, Chiayi, TaiwanTzu Chi Univ, Sch Med, Hualien, Taiwan
Lee, Moon-Sing
Hung, Shih-Kai
论文数: 0引用数: 0
h-index: 0
机构:
Tzu Chi Univ, Sch Med, Hualien, Taiwan
Buddhist Dalin Tzu Chi Gen Hosp, Dept Radiat Oncol, Chiayi, TaiwanTzu Chi Univ, Sch Med, Hualien, Taiwan
Hung, Shih-Kai
Yu, Chih-Chia
论文数: 0引用数: 0
h-index: 0
机构:
Buddhist Dalin Tzu Chi Gen Hosp, Dept Internal Med, Div Hematol Oncol, Chiayi, TaiwanTzu Chi Univ, Sch Med, Hualien, Taiwan
Yu, Chih-Chia
Su, Yu-Chieh
论文数: 0引用数: 0
h-index: 0
机构:
Tzu Chi Univ, Sch Med, Hualien, Taiwan
Buddhist Dalin Tzu Chi Gen Hosp, Dept Internal Med, Div Hematol Oncol, Chiayi, TaiwanTzu Chi Univ, Sch Med, Hualien, Taiwan
机构:
Sfantul Andrei Emergency Hosp Galati, ENT Dept, Galati 800578, Romania
Dunarea de Jos Univ Galati, Fac Med & Pharm, Galati 800010, RomaniaSfantul Andrei Emergency Hosp Galati, ENT Dept, Galati 800578, Romania
Iancu, Doriana
Fulga, Ana
论文数: 0引用数: 0
h-index: 0
机构:
Sfantul Andrei Emergency Hosp Galati, ENT Dept, Galati 800578, Romania
Dunarea de Jos Univ Galati, Fac Med & Pharm, Galati 800010, RomaniaSfantul Andrei Emergency Hosp Galati, ENT Dept, Galati 800578, Romania
Fulga, Ana
Vesa, Doina
论文数: 0引用数: 0
h-index: 0
机构:
Dunarea de Jos Univ Galati, Fac Med & Pharm, Galati 800010, RomaniaSfantul Andrei Emergency Hosp Galati, ENT Dept, Galati 800578, Romania
Vesa, Doina
Fulga, Iuliu
论文数: 0引用数: 0
h-index: 0
机构:
Dunarea de Jos Univ Galati, Fac Med & Pharm, Galati 800010, Romania
Sfantul Andrei Emergency Clin Hosp Galati, Dept Forens Med, Galati 800578, RomaniaSfantul Andrei Emergency Hosp Galati, ENT Dept, Galati 800578, Romania
Fulga, Iuliu
Tutunaru, Dana
论文数: 0引用数: 0
h-index: 0
机构:
Dunarea de Jos Univ Galati, Fac Med & Pharm, Galati 800010, RomaniaSfantul Andrei Emergency Hosp Galati, ENT Dept, Galati 800578, Romania
Tutunaru, Dana
Zenovia, Andrei
论文数: 0引用数: 0
h-index: 0
机构:
Cai Ferate Gen Hosp, Dept Otorhinolaryngol, Galati 800223, RomaniaSfantul Andrei Emergency Hosp Galati, ENT Dept, Galati 800578, Romania
Zenovia, Andrei
Piraianu, Alin Ionut
论文数: 0引用数: 0
h-index: 0
机构:
Dunarea de Jos Univ Galati, Fac Med & Pharm, Galati 800010, RomaniaSfantul Andrei Emergency Hosp Galati, ENT Dept, Galati 800578, Romania
Piraianu, Alin Ionut
Stamate, Elena
论文数: 0引用数: 0
h-index: 0
机构:
Emergency Univ Hosp Bucharest, Cardiol Dept, Bucharest 050098, RomaniaSfantul Andrei Emergency Hosp Galati, ENT Dept, Galati 800578, Romania
Stamate, Elena
Sterian, Corina
论文数: 0引用数: 0
h-index: 0
机构:
Danube Med Ctr, Braila 810197, RomaniaSfantul Andrei Emergency Hosp Galati, ENT Dept, Galati 800578, Romania
Sterian, Corina
Dimofte, Florentin
论文数: 0引用数: 0
h-index: 0
机构:
Dunarea de Jos Univ Galati, Fac Med & Pharm, Galati 800010, RomaniaSfantul Andrei Emergency Hosp Galati, ENT Dept, Galati 800578, Romania
Dimofte, Florentin
Badea, Mihail Alexandru
论文数: 0引用数: 0
h-index: 0
机构:
George Emil Palade Univ Med, Dept Microbiol, Pharm, Targu Mures 540139, RomaniaSfantul Andrei Emergency Hosp Galati, ENT Dept, Galati 800578, Romania
Badea, Mihail Alexandru
Tatu, Alin Laurentiu
论文数: 0引用数: 0
h-index: 0
机构:
Dunarea de Jos Univ Galati, Fac Med & Pharm, Galati 800010, Romania
Sfanta Cuvioasa Parascheva Hosp Infect Dis, Dept Dermatol, Galati 800179, Romania
Multidisciplinary Integrat Ctr Dermatol Interface, Galati 800179, RomaniaSfantul Andrei Emergency Hosp Galati, ENT Dept, Galati 800578, Romania
机构:
Leiden Med Ctr, Dept Otorhinolaryngol, NL-2300 RC Leiden, NetherlandsLeiden Med Ctr, Dept Otorhinolaryngol, NL-2300 RC Leiden, Netherlands
van Monsjou, Hester S.
Wreesmann, Volkert B.
论文数: 0引用数: 0
h-index: 0
机构:
Mem Sloan Kettering Canc Ctr, Head & Neck Serv, Dept Surg, New York, NY 10065 USALeiden Med Ctr, Dept Otorhinolaryngol, NL-2300 RC Leiden, Netherlands
机构:
Tzu Chi Univ, Sch Med, Hualien, Taiwan
Buddhist Dalin Tzu Chi Gen Hosp, Dept Otolaryngol, Chiayi, TaiwanTzu Chi Univ, Sch Med, Hualien, Taiwan
Lee, Ching-Chih
Ho, Hsu-Chueh
论文数: 0引用数: 0
h-index: 0
机构:
Tzu Chi Univ, Sch Med, Hualien, Taiwan
Buddhist Dalin Tzu Chi Gen Hosp, Dept Otolaryngol, Chiayi, TaiwanTzu Chi Univ, Sch Med, Hualien, Taiwan
Ho, Hsu-Chueh
Lee, Moon-Sing
论文数: 0引用数: 0
h-index: 0
机构:
Tzu Chi Univ, Sch Med, Hualien, Taiwan
Buddhist Dalin Tzu Chi Gen Hosp, Dept Radiat Oncol, Chiayi, TaiwanTzu Chi Univ, Sch Med, Hualien, Taiwan
Lee, Moon-Sing
Hung, Shih-Kai
论文数: 0引用数: 0
h-index: 0
机构:
Tzu Chi Univ, Sch Med, Hualien, Taiwan
Buddhist Dalin Tzu Chi Gen Hosp, Dept Radiat Oncol, Chiayi, TaiwanTzu Chi Univ, Sch Med, Hualien, Taiwan
Hung, Shih-Kai
Yu, Chih-Chia
论文数: 0引用数: 0
h-index: 0
机构:
Buddhist Dalin Tzu Chi Gen Hosp, Dept Internal Med, Div Hematol Oncol, Chiayi, TaiwanTzu Chi Univ, Sch Med, Hualien, Taiwan
Yu, Chih-Chia
Su, Yu-Chieh
论文数: 0引用数: 0
h-index: 0
机构:
Tzu Chi Univ, Sch Med, Hualien, Taiwan
Buddhist Dalin Tzu Chi Gen Hosp, Dept Internal Med, Div Hematol Oncol, Chiayi, TaiwanTzu Chi Univ, Sch Med, Hualien, Taiwan
机构:
Sfantul Andrei Emergency Hosp Galati, ENT Dept, Galati 800578, Romania
Dunarea de Jos Univ Galati, Fac Med & Pharm, Galati 800010, RomaniaSfantul Andrei Emergency Hosp Galati, ENT Dept, Galati 800578, Romania
Iancu, Doriana
Fulga, Ana
论文数: 0引用数: 0
h-index: 0
机构:
Sfantul Andrei Emergency Hosp Galati, ENT Dept, Galati 800578, Romania
Dunarea de Jos Univ Galati, Fac Med & Pharm, Galati 800010, RomaniaSfantul Andrei Emergency Hosp Galati, ENT Dept, Galati 800578, Romania
Fulga, Ana
Vesa, Doina
论文数: 0引用数: 0
h-index: 0
机构:
Dunarea de Jos Univ Galati, Fac Med & Pharm, Galati 800010, RomaniaSfantul Andrei Emergency Hosp Galati, ENT Dept, Galati 800578, Romania
Vesa, Doina
Fulga, Iuliu
论文数: 0引用数: 0
h-index: 0
机构:
Dunarea de Jos Univ Galati, Fac Med & Pharm, Galati 800010, Romania
Sfantul Andrei Emergency Clin Hosp Galati, Dept Forens Med, Galati 800578, RomaniaSfantul Andrei Emergency Hosp Galati, ENT Dept, Galati 800578, Romania
Fulga, Iuliu
Tutunaru, Dana
论文数: 0引用数: 0
h-index: 0
机构:
Dunarea de Jos Univ Galati, Fac Med & Pharm, Galati 800010, RomaniaSfantul Andrei Emergency Hosp Galati, ENT Dept, Galati 800578, Romania
Tutunaru, Dana
Zenovia, Andrei
论文数: 0引用数: 0
h-index: 0
机构:
Cai Ferate Gen Hosp, Dept Otorhinolaryngol, Galati 800223, RomaniaSfantul Andrei Emergency Hosp Galati, ENT Dept, Galati 800578, Romania
Zenovia, Andrei
Piraianu, Alin Ionut
论文数: 0引用数: 0
h-index: 0
机构:
Dunarea de Jos Univ Galati, Fac Med & Pharm, Galati 800010, RomaniaSfantul Andrei Emergency Hosp Galati, ENT Dept, Galati 800578, Romania
Piraianu, Alin Ionut
Stamate, Elena
论文数: 0引用数: 0
h-index: 0
机构:
Emergency Univ Hosp Bucharest, Cardiol Dept, Bucharest 050098, RomaniaSfantul Andrei Emergency Hosp Galati, ENT Dept, Galati 800578, Romania
Stamate, Elena
Sterian, Corina
论文数: 0引用数: 0
h-index: 0
机构:
Danube Med Ctr, Braila 810197, RomaniaSfantul Andrei Emergency Hosp Galati, ENT Dept, Galati 800578, Romania
Sterian, Corina
Dimofte, Florentin
论文数: 0引用数: 0
h-index: 0
机构:
Dunarea de Jos Univ Galati, Fac Med & Pharm, Galati 800010, RomaniaSfantul Andrei Emergency Hosp Galati, ENT Dept, Galati 800578, Romania
Dimofte, Florentin
Badea, Mihail Alexandru
论文数: 0引用数: 0
h-index: 0
机构:
George Emil Palade Univ Med, Dept Microbiol, Pharm, Targu Mures 540139, RomaniaSfantul Andrei Emergency Hosp Galati, ENT Dept, Galati 800578, Romania
Badea, Mihail Alexandru
Tatu, Alin Laurentiu
论文数: 0引用数: 0
h-index: 0
机构:
Dunarea de Jos Univ Galati, Fac Med & Pharm, Galati 800010, Romania
Sfanta Cuvioasa Parascheva Hosp Infect Dis, Dept Dermatol, Galati 800179, Romania
Multidisciplinary Integrat Ctr Dermatol Interface, Galati 800179, RomaniaSfantul Andrei Emergency Hosp Galati, ENT Dept, Galati 800578, Romania