Rapid rheological screening to identify conditions of biomaterial hydrogelation

被引：31

作者：

Schultz, Kelly M. ^{[1
,2
]}

Baldwin, Aaron D. ^{[3
,4
]}

Kiick, Kristi L. ^{[3
,4
]}

Furst, Eric M. ^{[1
,2
]}

机构：

[1] Univ Delaware, Dept Chem Engn, Newark, DE 19716 USA

[2] Univ Delaware, Ctr Mol & Engn Thermodynam, Newark, DE 19716 USA

[3] Univ Delaware, Dept Mat Sci & Engn, Newark, DE 19716 USA

[4] Univ Delaware, Delaware Biotechnol Inst, Newark, DE 19716 USA

来源：

SOFT MATTER | 2009年 / 5卷 / 04期

基金：

美国国家科学基金会; 美国国家卫生研究院;

关键词：

PEG HYDROGELS; MICRORHEOLOGY; MATRICES; GELATION;

D O I：

10.1039/b818178k

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

Hydrogels engineered for biomedical applications consist of numerous components, each of which can affect the material assembly and final mechanical properties. We present methods that rapidly generate rheological libraries to identify regimes of hydrogel assembly in a large composition parameter space. This method conserves both material and time, and leads to critical insight into assembly mechanisms and mechanics, which can then be used for further materials development and optimization.

引用

页码：740 / 742

页数：3

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