Patient-Specific Modeling of Hemodynamics: Supporting Surgical Planning in a Fontan Circulation Correction

被引:45
作者
van Bakel, Theodorus M. J. [1 ]
Lau, Kevin D. [1 ]
Hirsch-Romano, Jennifer [2 ]
Trimarchi, Santi [3 ]
Dorfman, Adam L. [2 ]
Figueroa, C. Alberto [1 ,4 ]
机构
[1] Univ Michigan, Dept Surg, Ann Arbor, MI 48109 USA
[2] Univ Michigan, CS Mott Childrens Hosp, Congenital Heart Ctr, Ann Arbor, MI 48109 USA
[3] Policlin San Donato IRCCS, Thorac Aort Res Ctr, San Donato Milanese, Italy
[4] Univ Michigan, Dept Biomed Engn, Ann Arbor, MI 48109 USA
基金
美国国家科学基金会; 欧洲研究理事会;
关键词
Computational fluid dynamics; Patient-specific modeling; Hemodynamics; Surgical planning; Pulmonary arteriovenous malformations; Single ventricle; PULMONARY ARTERIOVENOUS-MALFORMATIONS; CARDIAC-OUTPUT; BLOOD-FLOW; QUANTIFICATION; SIMULATION; VELOCITY;
D O I
10.1007/s12265-017-9781-x
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Computational fluid dynamics (CFD) is a modeling technique that enables calculation of the behavior of fluid flows in complex geometries. In cardiovascular medicine, CFD methods are being used to calculate patient-specific hemodynamics for a variety of applications, such as disease research, noninvasive diagnostics, medical device evaluation, and surgical planning. This paper provides a concise overview of the methods to perform patient-specific computational analyses using clinical data, followed by a case study where CFD-supported surgical planning is presented in a patient with Fontan circulation complicated by unilateral pulmonary arteriovenous malformations. In closing, the challenges for implementation and adoption of CFD modeling in clinical practice are discussed.
引用
收藏
页码:145 / 155
页数:11
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