Determination of organophosphorus pesticides and metabolites in cereal-based baby foods and wheat flour by means of ultrasound-assisted extraction and hollow-fiber liquid-phase microextraction prior to gas chromatography with nitrogen phosphorus detection

被引:50
作者
Angel Gonzalez-Curbelo, Miguel [1 ]
Hernandez-Borges, Javier [1 ]
Maria Borges-Miquel, Teresa [1 ]
Angel Rodriguez-Delgado, Miguel [1 ]
机构
[1] Univ La Laguna, Fac Quim, Dept Quim Anal Nutr & Bromatol, E-38206 Tenerife, Spain
关键词
Organophosphorus pesticides; Ultrasound-assisted extraction; Hollow-fiber liquid-phase microextraction; Cereal-based baby foods; Wheat flour; Gas chromatography-nitrogen phosphorus detection; QUADRUPOLE MASS-SPECTROMETRY; RESIDUE ANALYSIS; SAMPLE-PREPARATION; MEMBRANE; WATER;
D O I
10.1016/j.chroma.2013.05.081
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
A new method based on hollow-fiber liquid-phase microextraction (HF-LPME) has been developed for the determination of a group of organophosphorus pesticides, including some of their metabolites, in two commercial cereal-based baby foods and one wheat flour prior to gas chromatography-nitrogen phosphorus detection. Samples were first extracted by ultrasound-assisted extraction with acetonitrile (ACN) containing 1.25% (v/v) of formic acid. After evaporation and reconstitution in Milli-Q water, the HF-LPME procedure, using 1-octanol as extraction solvent, was applied followed by a desorption step in ACN, which clearly improved the performance of the technique. The effects of sample pH, ionic strength, stirring rate, extraction temperature and time as well as the desorption procedure were investigated. Under the optimum conditions that involved the extraction of the analytes from 10 mL of the water reconstituted extract at pH 7.0 containing 5% (w/v) of NaCl for 45 min at 960 rpm, the method was validated in terms of linearity, precision and accuracy. The limits of detection (LODs) were between 0.29 and 3.20 mu g/kg. The extraction of Milli-Q water, as an example of the applicability of the procedure to aqueous samples, allowed achieving LODs in the range 0.01-0.04 mu g/L. Such values, together with the ones achieved for the rest of the samples, are below or equal to the maximum residue limits specified by the European Union. (c) 2013 Elsevier B.V. All rights reserved.
引用
收藏
页码:166 / 174
页数:9
相关论文
共 30 条
  • [1] Validation of Two Variations of the QuEChERS Method for the Determination of Multiclass Pesticide Residues in Cereal-Based Infant Foods by LC-MS/MS
    Anagnostopoulos, Chris J.
    Sarli, Pipina Aplada
    Liapis, Konstantinos
    Haroutounian, Serko A.
    Miliadis, George E.
    [J]. FOOD ANALYTICAL METHODS, 2012, 5 (04) : 664 - 683
  • [2] Sample-preparation methods for pesticide-residue analysis in cereals and derivatives
    Angel Gonzalez-Curbelo, Miguel
    Herrera-Herrera, Antonio V.
    Ravelo-Perez, Lidia M.
    Hernandez-Borges, Javier
    [J]. TRAC-TRENDS IN ANALYTICAL CHEMISTRY, 2012, 38 : 32 - 51
  • [3] Pesticide residue analysis in cereal-based baby foods using multi-walled carbon nanotubes dispersive solid-phase extraction
    Angel Gonzalez-Curbelo, Miguel
    Asensio-Ramos, Maria
    Herrera-Herrera, Antonio V.
    Hernandez-Borges, Javier
    [J]. ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 2012, 404 (01) : 183 - 196
  • [4] Hollow-fiber liquid-phase microextraction for the determination of pesticides and metabolites in soils and water samples using HPLC and fluorescence detection
    Asensio-Ramos, Maria
    Hernandez-Borges, Javier
    Gonzalez-Hernandez, Guillermo
    Angel Rodriguez-Delgado, Miguel
    [J]. ELECTROPHORESIS, 2012, 33 (14) : 2184 - 2191
  • [5] Liquid phase microextraction applications in food analysis
    Asensio-Ramos, Maria
    Ravelo-Perez, Lidia M.
    Angel Gonzalez-Curbelo, Miguel
    Hernandez-Borges, Javier
    [J]. JOURNAL OF CHROMATOGRAPHY A, 2011, 1218 (42) : 7415 - 7437
  • [6] Hollow fiber-liquid-phase microextraction of fungicides from orange juices
    Barahona, Francisco
    Gjelstad, Astrid
    Pedersen-Bjergaard, Stig
    Rasmussen, Knut Einar
    [J]. JOURNAL OF CHROMATOGRAPHY A, 2010, 1217 (13) : 1989 - 1994
  • [7] Simultaneous liquid-liquid microextraction and polypropylene microporous membrane solid-phase extraction of organochlorine pesticides in water, tomato and strawberry samples
    Bedendo, Gizelle Cristina
    Carasek, Eduardo
    [J]. JOURNAL OF CHROMATOGRAPHY A, 2010, 1217 (01) : 7 - 13
  • [8] Use of automated direct sample introduction with analyte protectants in the GC-MS analysis of pesticide residues
    Cajka, T
    Mastovská, K
    Lehotay, SJ
    Hajslová, J
    [J]. JOURNAL OF SEPARATION SCIENCE, 2005, 28 (9-10) : 1048 - 1060
  • [9] Rapid analysis of multiple pesticide residues in fruit-based baby food using programmed temperature vaporiser injection-low-pressure gas chromatography-high-resolution time-of-flight mass spectrometry
    Cajka, Tomas
    Hajslova, Jana
    Lacina, Ondrej
    Mastovska, Katerina
    Lehotay, Steven J.
    [J]. JOURNAL OF CHROMATOGRAPHY A, 2008, 1186 (1-2) : 281 - 294
  • [10] Evaluation of cost-effective methods in the pesticide residue analysis of non-fatty baby foods
    Georgakopoulos, Panagiotis
    Mylona, Aggeliki
    Athanasopoulos, Panagiotis
    Drosinos, Eleftherios H.
    Skandamis, Panagiotis N.
    [J]. FOOD CHEMISTRY, 2009, 115 (03) : 1164 - 1169